نتایج جستجو برای: moderate persistent asthma
تعداد نتایج: 335223 فیلتر نتایج به سال:
Cysteinyl leukotrienes act as potent bronchoconstrictors and are part of the inflammatory cascade initiated during an asthma attack. They are produced – along with other inflammatory agents – by inflammatory cells, including mast cells and eosinophils. Leukotriene modifiers act by either inhibiting leukotriene formation (zileuton) or as leukotriene receptor antagonists (LTRAs; montelukast and z...
BACKGROUND PCR studies have demonstrated evidence of Mycoplasma pneumoniae and Chlamydophila pneumoniae in the lower airways of patients with asthma. OBJECTIVE To test the hypothesis that clarithromycin would improve asthma control in individuals with mild-to-moderate persistent asthma that was not well controlled despite treatment with low-dose inhaled corticosteroids. METHODS Adults with ...
Moderate-to-severe asthma has a substantial impact on the health-related quality of life (HR-QOL) of the patients. Cordyceps sinensis is a traditional Chinese medicine that is evaluated clinically for the treatment of many diseases, such as chronic allograft nephropathy, diabetic kidney disease, and lung fibrosis. In order to investigate the effects of Cordyceps sinensis on patients with modera...
RATIONALE Airway inflammation in asthma is associated with increased activated CD25(+) T cells, IL-2, and soluble IL-2 receptors (IL-2Rs). OBJECTIVES A randomized, double-blinded, placebo-controlled study was used to evaluate the safety and efficacy of daclizumab, a humanized IgG1 monoclonal antibody against the IL-2R alpha chain (CD25) of activated lymphocytes, in adults with moderate to sev...
cromolyn sodium, a mast cell stabilizing agent, provides an immediate protective effect against the exercise-induced bronchoconstriction while being used before the exercise. however, cromolyn is ineffective in reversing asthmatic bronchospasm; it is used as a maintenance therapy and has a prophylactic role in chronic asthma. the purpose of this study was to determine the extent of change in...
PURPOSE Omalizumab is the preferred add-on therapy for patients with moderate-to-severe persistent allergic asthma and has demonstrated efficacy and safety in various ethnicities. This study evaluated the efficacy and safety of omalizumab in Chinese patients with moderate-to-severe allergic asthma. METHODS This randomized, double-blind, parallel-group, placebo-controlled, phase III study asse...
Despite an improved understanding of asthma and the many new treatments available for its control, a surprising number of patients appear refractory or unresponsive to the best management. Most patients with asthma have mild or moderate disease that responds well to simple treatments. Unfortunately, a proportion of patients suffer persistent symptoms, have recurrent exacerbations or have sub-op...
Asthma is an inflammatory condition characterized by the involvement of several mediators, including reactive oxygen species. The aim of the present study was to investigate the superoxide release and cellular glutathione peroxidase (cGPx) activity in peripheral blood granulocytes and monocytes from children and adolescents with atopic asthma. Forty-four patients were selected and classified as...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید