depending on the sensitivity of the method, deletions may be detected at the majority (60-65 %) of duchenne/becker muscular dystrophy (dmd/bmd) cases. duplications may be seen in approximately 5 -10% and the remaining mutations are point mutations, intronic deletions, exonic insersions of repetetive sequences and combinations of all. severity of the disease does not correlate with the size of t...

Circulating tumor DNA (ctDNA) is emerging as a biomarker to detect molecular evidence of residual disease and predict recurrence in patients with colorectal cancer the adjuvant setting. Treatment paradigms have been evolving stage II III rectal total neoadjuvant therapy (TNT). Prospective evaluation, feasibility utility using ctDNA during clinical practice has limited date. In this retrospectiv...

Tubercular uveitis (TBU) is a common cause of infectious uveitis in countries where tuberculosis is endemic. Molecular diagnostic techniques are the cornerstone of diagnosis as of now, as culture positivity has never been reported to date. With increasing reports of multidrug-resistant tuberculosis (MDR TB) from various extrapulmonary sites and in the light of a recent case report (1), there is...

Adjuvant CAPE is the standard-of-care (SoC) in eTNBC pts with incomplete response to anthracycline-based NAT. Presence of ctDNA following standard therapy early breast cancer associated poor relapse-free survival (RFS). Here, we evaluated rates detection before, during and after adjuvant CAPE. Pts residual disease NAT receiving for 6 months (+/- pembrolizumab) were enrolled 2 separate, prospect...

Contaminated food and water are usual vehicles for bacterial pathogens transmission. According to EFSA they promote foodborne illness. Salmonella sp., Campylobacter sp., Listeria monocytogenes, Escherichia coli and Staphylococcus aureus are the most foodborne pathogens reported. Bacterial contamination levels remain at high level, particularly in Europe, despite regulatory efforts to address th...

Food poisoning by staphylococcal enterotoxins (SE) is a major cause of foodborne illness, often associated with coagulase-positive staphylococci (CPS). The increase in the number methicillin-resistant Staphylococcus aureus (MRSA) strains another problem CPS. However, reports association SE and coagulase-negative (CNS) are beginning to re-emerge. In this context, aim study investigate presence e...