Microplastics (MPs), commonly defined as particles less than 5 mm, are a persistent ubiquitous anthropogenic contaminant that can be found in every environment, making it global environmental, health, and socioeconomic problem. Due to their high surface area, MPs adsorb toxic pollutants become bioavailable organisms upon ingestion they often mistaken for food leading biomagnification (Bule et a...

2016; 115: 311-323. Microparticles (MPs) represent extracellular vesicles that are released from their parental cell by budding of the plasma membrane and are known to harbour an opulent spectrum of bioactive substances including microRNA (miRNA). As a multitude of induction pathways together with inclusive and exclusive sorting mechanisms are operative during the generation of MPs, the molecul...

Plant viruses move through plasmodesmata (PD) either as nucleoprotein complexes (NPCs) or as tubule-guided encapsidated particles with the help of movement proteins (MPs). To explore how and why MPs specialize in one mechanism or the other, we tested the exchangeability of MPs encoded by DNA and RNA virus genomes by means of an engineered alfalfa mosaic virus (AMV) system. We show that Caulimov...

In conjunction with matrix proteins, stem cell factor (SCF) plays an important role in the migration of melanocyte precursors (MPs) derived from the mouse embryo. However, no studies have demonstrated an effect of SCF on human follicular MPs migration in vitro. In this report, first we demonstrate the immature state of the follicular MPs. Then cell attachment rate was measured by 3-(4,5-dimethy...

BACKGROUND Microparticles (MPs) are small vesicles released during cell activation or apoptosis. They are involved in coagulation, inflammation and vascular dysfunction in several diseases. We characterized circulating MPs from Crohn's Disease (CD) patients and evaluated their effects on endothelial function and vascular reactivity after in vivo injection into mice. METHODS Circulating MPs an...

MOTIVATION Moonlighting proteins (MPs) show multiple cellular functions within a single polypeptide chain. To understand the overall landscape of their functional diversity, it is important to establish a computational method that can identify MPs on a genome scale. Previously, we have systematically characterized MPs using functional and omics-scale information. In this work, we develop a comp...

Literature addressing master production scheduling (MPS) typically focuses on the development of sophisticated MPS methods with the expectation that these methods will result in feasible plans and improved performance. However, empirical evidence showing that sophisticated methods are better than simpler ones remains scarce, and companies have reported difficulties with using sophisticated plan...

BACKGROUND Undiagnosed patients with the attenuated form of mucopolysaccharidosis (MPS) type I often have joint symptoms in childhood that prompt referral to a rheumatologist. A survey conducted by Genzyme Corporation of 60 European and Canadian rheumatologists and pediatric rheumatologists demonstrated that < 20% recognized signs and symptoms of MPS I or could identify appropriate diagnosis te...