' 'One picture is worth more than a thousand words''. The validity of this expression, which is a leitmotiv in the publicity sector, is not limited to the strategy underlying advertisements. It certainly also applies to the commanding role images play in diagnostic medicine. To draw lines of development in imaging instruments, one must start where the arsenal of nuclear medicine equipment stand...

metastatic survey of the patients with known primary malignancies with bone scan is one of the most common studies in nuclear medicine. unfortunately the conventional planar bone scan has a very low specificity for differentiating benign from malignant lesions especially in the spinal column. in this study, we compared the specificity of spect imaging and conventional planar bone scan. we studi...

The growth of molecular imaging heightens the promise of clinical nuclear medicine as a tool for individualization of patient care and for improvement of health-care outcomes. Together with greater use of integrated structure-function imaging, clinical nuclear medicine reaches beyond traditional specialty borders into diagnostic radiology and oncology. Yet, there are concerns about the future o...

  Objective(s): The objective of this study was to evaluate the performance and utility of 99mTc HYNIC-TOC planar scintigraphy and SPECT/CT in the diagnosis, staging and management of gastroenteropancreatic neuroendocrine tumors (GPNETs). Methods: 22 patients (median age, 46 years) with histologically proven gastroentero-pancreatic NETs underwent 99mTc HYNIC-TOC whole body scintigraphy and regi...

Introduction: A noninvasive method of detecting exposure of phosphatidylserine (PS) on the external surface of the plasma membrane such as nuclear imaging could assist the diagnosis and therapy of apoptosis related pathologies. The most studied imaging agent for apoptosis is Annexin V so far. Because of limitations of Annexin V other agents have been introduced such as small peptides and molecu...

Since the introduction of the need to use imaging for the monitoring of cardiomyopathies and particularly ischemic cardiomyopathies in international guidelines, articles reporting the place, the accuracy and the prognostic impact of cardiac imaging have grown exponentially. During 2015, the European Journal of Nuclear Medicine and Molecular Imaging published selected pre-clinical, technical and...

Introduction: A noninvasive method of detecting exposure of phosphatidylserine (PS) on the external surface of the plasma membrane such as nuclear imaging could assist the diagnosis and therapy of apoptosis related pathologies. The most studied imaging agent for apoptosis is Annexin V so far. Because of limitations of Annexin V other agents have been introduced such as small peptides and molecu...

1Division of Molecular Imaging and Radiochemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University, Mannheim, Germany; 2McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Canada; 3Division of Biomedical Chemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of ...