نتایج جستجو برای: onset type load
تعداد نتایج: 1625129 فیلتر نتایج به سال:
AbstractObjectives: To assess the impact of attention deficit hyperactivity disorder (ADHD) on clinical characteristics of bipolar disorder (BPD) in hospitalized children and adolescents. Method: Clinical characteristics of twenty 6-18 years old children and adolescents with BPD was assessed and compared in two groups of patients with or without ADHD, using K-SADS clinical interview and the cl...
Transient epileptic amnesia (TEA) is a specific type of temporal lobe seizure involving the hippocampus and the parahippocampal gyrus, which can be recognized with now published criteria. The etiology of TEA is still under debate and probably not unique. Apart from rare patients showing structural lesions on brain MRI, microvascular brain load and/or immune-mediated neuronal aggression have bee...
Linkage studies have suggested a susceptibility locus for late-onset Alzheimer's disease (LOAD) on chromosome 21. A functional candidate gene in this region is the beta-amyloid precursor protein (APP) gene. Previously, coding mutations in APP have been associated with early onset Alzheimer's Disease (EOAD). Three copies of APP are associated with AD pathology in Down's syndrome and in EOAD, sug...
The variations of SORCS1 gene may play potential key roles in late-onset Alzheimer's disease (LOAD). To evaluate the relationship between the polymorphism of SORCS1 gene and LOAD in the ethnic Han Chinese, we conducted a case-control study to investigate the association between the single-nucleotide polymorphisms (SNPs) in intron 1 of SORCS1 and LOAD in Chinese Han population. Six reported SNPs...
Parkinson’s disease (PD) is a prevalent neurodegenerative disease that usually affects individuals over 50 years of age. Age at onset in a small subset of PD cases is considerably lower, and these are considered early-onset PD (EOPD) patients. Most PD cases appear sporadic, but approximately 15% are familial, and some of the familial cases exhibit Mendelian inheritance. Genetic analysis of fami...
Background: Epilepsy is considered as one of the most important disorders in neurology. Temporal lobe epilepsy is a form of epilepsy including two main types of mesial and lateral (neocortex). Objectives: Determination and comparison of electroencephalogram (EEG) pattern in the ictal and interictal phases of mesial and lateral temporal lobe epilepsy. Materials and Methods: This cross-sectiona...
background: temporal variation of stroke onset is suggested in some studies contained somewhat varieties. it is proposed that some predisposing changes occur in some ascertained times consequently resulted in stroke occurrence in some special times. objective: to determine the circadian and circaseptan variation of stroke onset. materials and methods: this cross sectional study was conducted fr...
The genetics of complex disease produce alterations in the molecular interactions of cellular pathways whose collective effect may become clear through the organized structure of molecular networks. To characterize molecular systems associated with late-onset Alzheimer's disease (LOAD), we constructed gene-regulatory networks in 1,647 postmortem brain tissues from LOAD patients and nondemented ...
Mutations in the ROMK1 potassium channel gene (KCNJ1) cause antenatal/neonatal Bartter syndrome type II (aBS II), a renal disorder that begins in utero, accounting for the polyhydramnios and premature delivery that is typical in affected infants, who develop massive renal salt wasting, hypokalaemic metabolic alkalosis, secondary hyperreninaemic hyperaldosteronism, hypercalciuria and nephrocalci...
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