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سیستم هیستامینرژیک مرکزی دارای تاثیرات تنظیمی بر رفتارهای شبه اضطرابی هم در حیوانات و هم در انسان است. این تاثیرات از طریق رسپتور h1 و h2 میانجیگری میشود. تست epm(elevatd plus-maze( برای بررسی تاثیرات اضطراب زایی یا اضطراب زدایی داروها در جوندگان بکار میرود. شواهد نشان می دهند که فعالیت (bnst) bed nucleus the stria terminalis رفتار شبه اضطرابی را در انسانها و حیوانات تنظیم می کند. در مطالعه حاض...
In the Methods section, there is an error in the first equation in the first paragraph. Please view the complete, correct equation here: dE dt ¼ f max L K L þ L À m À uðtÞ; dL dt ¼ au t ð Þ À m L L open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author...
Introduction: Lepidium draba L (L. draba) is one of the most valuable medicinal plants belonging to the nightshade family. This study was designed to evaluate anxiolytic effects of different doses of the methanolic extract of L. draba and also the role of benzodiazepine receptors. Method: In this study, 48 male mice weighing 25-30 g were used. The selected mice were randomly divided into 6 gro...
Background: Hepatitis delta virus (HDV) is a subviral human pathogen that exploits host RNA editing activity to produce two essential forms of the sole viral protein, hepatitis delta antigen (HDAg). Editing at the amber/W site of HDV antigenomic RNA leads to the production of the large form (L-HDAg), which is required for RNA packaging. Methods: In this study, PCR-based site-directed mutagen...
Open angle glaucoma (OAG) is a complex disorder with varying etiologies due to multiple genes and environmental effects. This genetic heterogeneity can confound efforts to map loci. Increased homogeneity in a sample can be achieved using either ordered subset analysis (OSA) which groups families, or individual OSA (IOSA), which groups individuals based on disease related covariates. Recently, G...
Pseudomonas aeruginosa DQ8, which was isolated from the crude oil polluted soil in the Daqing oilfield of China, can efficiently degrade diesel, crude oil, n-alkanes, and polycyclic aromatic hydrocarbons (PAHs). Here, we present a 6.8-Mb assembly of its genome sequence. We have annotated 23 coding sequences (CDSs) responsible for catabolism of n-alkanes and PAHs.
background: hepatitis delta virus (hdv) is a subviral human pathogen that exploits host rna editing activity to produce two essential forms of the sole viral protein, hepatitis delta antigen (hdag). editing at the amber/w site of hdv antigenomic rna leads to the production of the large form (l-hdag), which is required for rna packaging. methods: in this study, pcr-based site-directed mutagenesi...
Among the techniques for the creation of photorealistic virtual organisms, particularly plants, and in scientific models of vegetation structure, rule-based specifications (formal grammars) play a prominent role. Lindenmayer systems (L-systems) are the most widespread formalism of this sort, but certain types of graph grammars, combined with standard object-oriented programming, offer even more...
The rice endophyte Pantoea ananatis AMG521 shows several plant growth-promoting properties and promotes rice yield increases. Its draft genome was estimated at 4,891,568 bp with 4,704 coding sequences (CDS). The genome encodes genes for N-acylhomoserine lactone (AHL) synthases, AHL hydrolases, hyperadherence (yidQ, yidP, and yidR), fusaric acid resistance, and oxidation of lignin, highlighting ...
We study the maximum possible number f(k, l) of intersections of the boundaries of a simple k-gon with a simple l-gon in the plane for k, l ≥ 3. To determine the number f(k, l) is quite easy and known when k or l is even but still remains open for k and l both odd. We improve (for k ≤ l) the easy upper bound kl − l to kl − ⌈k/6⌉ − l and obtain exact bounds for k = 5 (f(5, l) = 4l − 2) in this c...
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