Background: In case of comple transection facial nerve, it is unclear whether or not corticosteroids will be beneficial after nerve neurorrhaphy.
 Aim: The purpose this systematic review was to determine are effective in promoting regeneration and functional recovery following complete Methods: Randomized controlled trials on human animal models from Ovid MEDLINE EMBASE that studied the ef...

purpose : to report two patients with spontaneous scleral perforation and bleb formation associated with marfan syndrome (mfs) which one of them also showed bilateral optic nerve dural ectasia. case reports : an 11-year-old girl was referred with progressive myopia. past medical history was negative. slit-lamp examination revealed bilateral scleral thinning and perforation with bleb formation, ...

introduction penetration of a bicycle brake handle into the orbit is a rare and serious type of trauma. globe subluxation due to such trauma has not been previously reported. case presentation a 10-year-old girl presented after falling from a bicycle, which resulted in the handbrake penetrating her right upper eyelid. on examination, the globe was subluxated anteriorly, there was no light perce...

Previous work suggested that brain NGF acts locally on cells adjacent to sites of synthesis, in addition to any putative actions on distant, projecting perikarya. To define the basis of local action, we used a sensitive nuclease protection assay to identify cells expressing the NGF gene in vivo and in vitro. In addition to neurons, glia from a variety of developing brain areas synthesized NGF m...

The distributions of substance P-like immunoreactivity (SPLI) and leucine-enkephalin-like immunoreactivity (LENKLI) in subnucleus caudalis of normal adult rats were compared with those observed in the adult rats that sustained transection of the infraorbital (IO) nerve either on the day of birth or in adulthood. All immunocytochemical experiments in the neonatally nerve damaged rats were carrie...

introduction: elevated intracranial pressure (icp) is a major and potentially lethal disorder in patients admitted to the emergency department (ed). several methods are being used to investigate for elevated icp. here we assessed and compared the diagnostic accuracy of two existing tools of ophthalmoscopy and optic nerve ultrasonography in detection of elevated icp. methods: 131 participants wi...

PURPOSE This study aimed to investigate the neuroprotective effect of resveratrol in an optic nerve transection (ONT) model and to identify the neuroprotective mechanism of resveratrol in retinal ganglion cells (RGCs). METHODS ONT and retrograde labeling were performed in Sprague-Dawley rats. Various concentrations of resveratrol were injected intravitreally immediately after ONT. The number ...

The Down syndrome cell adhesion molecule (DSCAM), an immunoglobulin (Ig) superfamily member, was first identified from human and subsequently isolated from both vertebrates and invertebrates. Recent studies have shown that the DSCAM molecule serves diverse functions in neurodevelopment, such as axon guidance and neuronal migration. Most studies on DSCAM, however, have focused on mammals and art...