background: hydroxymethylglutaryl‑coenzyme a reductase inhibitors (statins) are antihyperlipidemic drugs with an established efficacy in stabilizing atherosclerotic plaques and preventing atherogenesis and reducing cardiovascular events. the purpose of this study was to determine the effect of simvastatin on serum vitamin d status in dyslipidemic patients as vitamin d status has an impact on mo...

background:childhood zinc deficiency is a common problem in many developing countries where people rely mainly on plant based diets with low zinc contents. zinc supplementation is one of strategies to combat zinc deficiency and its consequences in children. the aim of this community trial was to examine the effect of zinc supplementation on the linear growth of children 6-24 months of age and t...

the activity and efficacy of iranian synthesized imidocarb dipropionate (imidorazi) has been tested against babesia ovis infection in experimentally and naturally affected sheep. the results indicated that the drug is effective and could be used for treatment of sheep and goats babesiosis. the effectiveness of imidorazi is also similar to the imizol (imidocarb dipropionate) imported from abroad.

conclusions barberry supplementation reduces oxidative burden in patients with metabolic syndrome. results there was no significant difference between the groups regarding their baseline pab values (p = 0.32). a significant decrease in pab was observed in the barberry group (p = 0.022), whilst there was no significant change in the control group (p = 0.18). the magnitude of change in pab during...

dna vaccination has been developed as a noteworthy immunotherapeutic approach for the battle against many serious challenges to human and animal safety, including infectious illnesses, autoimmunity, allergy and cancer. clinical trials prepare chances to examine whether dna vaccines can fulfill their final aim of demonstrating efficiency in treating humans. today, anticancer dna vaccines are qui...

randomization is an essential component of sound clinical trials which prevents selection biases and helps in blinding the allocations. randomization is a process by which subsequent subjects enrolled into trial groups only by chance which is essentially eliminates selection biases. a serious consequence of randomization is severe imbalance among treatment groups with respect to some prognostic...

objective: depression is a major health problem, which is not only underrecognized and undertreated, but is also associated with significant morbidity and mortality. it has been suggested that combination therapy rapidly reduces depressive symptoms in patients with moderate to severe depression and is more effective than monotherapy; but this suggestion remains controversial. serotonergic and n...