Antigenic components of the yeast extract of Paracoccidioides brasiliensis Linder 2511 cultured for 3, 8, 20, 30, and 60 days were examined by the Western blot (immunoblot) technique. The 3-day extract was chosen for characterization of the antigenic components because its stability did not vary with time and it contained all antigens identified by patient sera. Antibodies to cross-reacting ant...

Many reports have been published both in Brazil and abroad on the therapeutic results 12.5,7.8,9,10,11,12 and the side effects 3,4,14 of these drugs. SAMPAIO13 and DILLON6 concluded cn the superiority of amphotericin B when compared to separately administered sulfonamides. No studies, however, have been carried out to compare the therapeutic results obtained with amphotericin B alone and associ...

A two year-old female child was admitted at the Pediatric Intensive Care Unit in a septic shock associated with a lymphoproliferative syndrome, with history of fever, adynamia and weight loss during the last two months. On admission, the main clinical and laboratory manifestations were: pallor, jaundice, disseminated enlarged lymph nodes, hepatosplenomegaly, crusted warts on face, anemia, eosin...

A previously healthy, 52-year-old woman presented with a nine months history of low fever and weight loss (> 30 kg). Physical examination disclosed generalized lymphadenopathy, skin lesions, abdominal distension, mild tachypnea and a left breast mass. Laboratory tests showed anemia; (prerenal) kidney injury, low serum albumin level; and negative serology for HIV and viral hepatitis. Computed to...

1 Doutor em Medicina Otorrinolaringologia (Professor adjunto e Chefe do Serviço de Otorrinolaringologia, Hospital das Clínicas, Universidade Federal de Goiás). 2 Doutora em Ciências da Saúde. (Fonoaudióloga Epidemiologista. Serviço de Otorrinolaringologia, Hospital das Clínicas, Universidade Federal de Goiás, Goiânia, GO). 3 Otorrinolaringologista. (Médica otorrinolaringologista. Hospital das C...

Paracoccidioidomycosis is a chronic, subacute or rarely acute mycosis, with visceral and cutaneous involvement. It is potentially fatal. Children account for about 5-10% of cases. In this study, we describe the relevance of discussing possible differential diagnoses as well as the importance of early treatment.