Periapical inflammatory responses occur as a consequence of bacterial infection of the dental pulp, as a result of caries, trauma, or iatrogenic insult. Periapical inflammation stimulates the formation of granulomas and cysts, with the destruction of bone. These inflammatory responses are complex and consist of diverse elements. Immediate-type responses--including vasodilatation, increased vasc...

BACKGROUND Analyze the most important prognostic factors when performing periapical surgery and compare the success rates of distinct authors. INTRODUCTION Periapical surgery is an approach to treat non-healing periapical lesions and it should be viewed as an extension of endodontic treatment and not as a separate entity. MATERIAL AND METHODS A search of articles published in Cochrane, PubM...

Teeth may require further management following root canal treatment because of persisting or new apical pathosis. Management must be based on the diagnosis of the presenting condition and the history of the previous treatment, particularly in relation to when it was completed. Most root-filled teeth with periapical pathosis should be re-treated in the first instance via a conventional orthograd...

The presence of immunoreactive cells in periapical inflammatory lesions suggests that immune responses participate in the disease process. The purpose of this study was to determine the presence and concentration of immunoglobulins in the supernatant fluids of explant cultures of periapical lesions. Ninety periapical lesions that had been contiguous with the apex of a root were removed and main...

Objective. Periapical periodontitis is an infectious and inflammatory disease of the periapical tissues caused by oral bacteria invading the root canal. In the present study, profiling of the microbiota in infected root canals was performed using anaerobic culture and molecular biological techniques for bacterial identification. Methods. Informed consent was obtained from all subjects (age rang...

AIM To investigate the probability of and factors influencing periapical status of teeth following primary (1°RCTx) or secondary (2°RCTx) root canal treatment. METHODOLOGY This prospective study involved annual clinical and radiographic follow-up of 1°RCTx (1170 roots, 702 teeth and 534 patients) or 2°RCTx (1314 roots, 750 teeth and 559 patients) carried out by Endodontic postgraduate student...

Cone beam computed tomography (CBCT) is a recent three-dimensional (3D) radiographic imaging modality used for the accurate diagnosis, management and follow-up of endodontic problems. In tooth with open apex and periapical lesion, the use of new obturation material such as white mineral trioxide aggregate (wMTA) facilitates faster and more predictable closure of root apex and periapical healing...

Context: The essential role of a general dental practitioner is recognizing the nature of the oral cavity lesions. Periapical lesions, which are observed in radiographs of patients, may have odontogenic or nonodontogenic origins. This review aimed to study differential diagnosis of common and important periapical lesions. Evidence Acquisition: English-language literature were searched by manual...