The tooth is a vertebrate-specific organ that deve]ops through a series of reciprocal interactions between epithelium and mesenchyme. In this process, the neural crest (NC) cells participate in tooth development. NC cells are multipotent cells that are generated from the IHteral ridge of the dorsal neural tube during the early stuges of embryogenesis. NC cells migrate into various tissues, wher...

Childhood has been recognized as high-risk period for dental injuries and intrusion is one of the most common types of trauma to primary dentition. These injuries require the dentist to carefully examine not only the damaged tooth but possible sequelae to the permanent tooth germ and the overall health of the child. The present case report describes the treatment of a 3 years old child with com...

Dentigerous cyst is a type of odontogenic cysts and generally occurs in the ages of twenties or thirties. Dentigerous cyst always includes a tooth which cannot complete the eruption process and occurs around the crown by the fluid accumulation between the layers of enamel organ. In rare cases, dentigerous cyst occurs in the first decade of life and develops in an immature permanent tooth as a r...

A case is presented which demonstrates the incomplete transposition of a posterior tooth. In this case, the path of eruption of an abnormally angulated developing mandibular second premolar was diverted distally following the extraction of the adjacent first

The purpose of this article is to review the principles of case management of impacted mandibular premolars and to illustrate their potential to respond well to treatment. Although the scope of treatment may be influenced by the patient"s age, past dental history, severity of impaction, dentoalveolar development and root form, the 2 case reports demonstrate the inherent potential for good treat...

Supernumerary teeth are among the most common dental anomalies affecting the primary and permanent dentition. They are usually found in the anterior maxilla and occur infrequently in the primary dentition. The purpose of this paper was to report a case diagnosed with primary supernumerary tooth in the primary second molar region. The crown and root shape of the primary supernumerary tooth resem...

This case report describes the multidisciplinary management of subgingival horizontal crown-root fracture of an immature permanent maxillary central incisor in a 10-year-old boy. After removal of the fractured fragment, pulpotomy was performed within 48 h from the injury to promote apexogenesis. The tooth was orthodontically extruded until the fracture line was located above the alveolar bone l...

The etiology of tooth agenesis may be related to several factors, among them, the genetic alterations that play a fundamental role in the development of this dental anomaly, so that knowledge about it helps the clinician to have a greater understanding of their patients. Thus, the aim of this study was to report the case of a nonsyndromic child, with tooth agenesis of one premolar, three first ...

Teeth and denticles belong to a specialized class of mineralizing epithelial appendages called odontodes. Although homology of oral teeth in jawed vertebrates is well supported, the evolutionary origin of teeth and their relationship with other odontode types is less clear. We compared the cellular and molecular mechanisms directing development of teeth and skin denticles in sharks, where both ...