BACKGROUND AND AIM To assess the effectiveness of the potential advantages with 3-dimensional-based treatment planning versus 2-dimensional pelvic bone-based treatment planning in patients with rectal cancer, controlled for clinical stage. METHODS AND MATERIALS Areas at risk from computed tomography in 30 patients were delineated: mesorectum, presacral, internal iliac, obturator and external ...

Extranodal natural killer/T-cell lymphoma (ENKTL), nasal type, is a rare form of non-Hodgkin lymphoma. Treatment of ENKTL primarily relies on radiation; thus, proper delineation of target volumes is critical. Currently, the ideal modalities for delineation of gross tumor volume for ENKTL are unknown. We describe three consecutive cases of localized ENKTL that presented to the Nova Scotia Cancer...

We compared the dose conformity, homogeneity, dose to organs at risk, and remaining volume at risk of two radiotherapy techniques --stereotactic body radiotherapy and intensity-modulated radiotherapy (IMRT) to deliver hypofractionated radiotherapy in organ-confined prostate cancer. Eleven successive patients treated on the CyberKnife stereotactic robotic radiosurgical system were taken up for t...

In the thorax, the extent of tumor may be more accurately defined with the addition of (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET) to computed tomography (CT). This led to the increased utility of FDG-PET or PET/CT in the treatment planning of radiotherapy for non-small cell lung cancer (NSCLC). The inclusion of FDG-PET information in target volume delineation not only imp...

PURPOSE The purpose of the present study was to quantify the inter-fractional motion of the rectum and the rectal and bladder volumes using CBCT scans taken during chemoradiation therapy (CRT) for rectal cancer. Also, assessment was made for a better margin for simultaneous integrated boost - intensity modulated radiation therapy (SIB-IMRT) for rectal cancer. METHODS AND MATERIALS There were ...

This paper reviews efforts of incorporating FDG based PET/CT data into target volume delineation for radiotherapy treatment planning. Relationship between PET-based and CT-based volumes generally suffer from poor correlation between the two image data sets, expressed in terms of large statistical variation in gross tumor volume ratios irrespective of the thresholding method used. Future of biol...

This study reviewed prostate volumetric-modulated arc therapy (VMAT) plans with intensity-modulated radiotherapy (IMRT) plans after prostate IMRT technique was replaced by VMAT in an institution. Characterizations of dosimetry and radiobiological variation in prostate were determined based on treatment plans of 40 prostate IMRT patients (planning target volume = 77.8-335 cm(3)) and 50 VMAT pati...

Introduction: Stereotactic Gamma Knife radiosurgery has been widely used for treating brain tumors. The scattered radiation outside of treatment field (peripheral dose) can induce the secondary cancer to specific organ. This paper investigated the absorbed dose to eyes, thyroid, heart, lung, breast and colon using a Monte Carlo technique for Mird phantom. We also study the ef...

Time-averaged intreatment prostate localization errors were calculated, for the first time, by three-dimensional prostate image cross-correlation between planning CT and intrafraction kilovoltage cone-beam CT (CBCT) during volumetric modulated arc therapy (VMAT). The intrafraction CBCT volume was reconstructed by an inhouse software after acquiring cine-mode projection images during VMAT delive...