BACKGROUND Maltitol is a sugar alcohol that is frequently used as a noncaloric sweetener, although it is also used as an excipient, a plasticizer in gelatin capsules, and an emollient. It has not been previously described as an agent involved in immediate hypersensitivity reactions. METHODS We report on an anaphylactoid reaction with pharyngeal occlusion suffered by a 60-year-old man after in...

The purpose of the present research was to develop a fast and rapidly dissolving polymeric sublingual thin film vildagliptin due its simplicity use as an alternative oral disintegrating tablets better compliance for diabetic patients. Nine different formulations (F1-F9) films were produced using diverse concentrations polymer A plasticizer B by solvent casting method. Several physicochemical pr...

A FI Zr-based catalyst of bis[N-(3,5-dicumylsalicylidene)-2′,6′­diisopropylanilinato]zirconium(IV) dichloride was prepared and used for polymerization of ethylene. The effects of reaction conditions on the polymerization were examined in detail. The increase in ethylene pressure and rise in polymerization temperature up to 35 oC were favorable for catalyst/MAO to raise the catalytic activity as...

Objective(S): The chitosan - Fe3O4 core - shell nanoparticles were synthesized. The nanoparticles should be coated properly in the shape of core-shell, so that they remain hidden from the body's immune system after coating. Effects of different molecular weight in coating were investigated. Methods: Nanoparticles coated with low and ...

microstructural investigation of low molecular weight 1,4-polybutadiene (1,4-pbd) was studied by 1h and 13c nuclear magnetic resonance spectroscopy (nmr). the isomer contents of 1,4-cis, 1,4-trans and 1,2- vinyl in polybutadiene microstructure were determined. the number average molecular weight for low molecular weight polybutadiene was measured by nmr techniques and comparison was made with g...

The effects of low molecular weight diluents (namely water and glycerol) on the nanostructure and thermodynamic state of low water content gelatin matrices are explored systematically by combining positron annihilation lifetime spectroscopy (PALS) with calorimetric measurements. Bovine gelatin matrices with a variation in the glycerol content (0–10wt.%) are equilibrated in a range of water acti...

Cyclodextrins (CDs) have been extensively studied as drug delivery carriers through host–guest interactions. CD-based poly(pseudo)rotaxanes, which are composed of one or more CD rings threading on the polymer chain with or without bulky groups (or stoppers), have attracted great interest in the development of supramolecular biomaterials. Poly(ethylene oxide) (PEO) is a water-soluble, biocompati...

   High strength and elastic biodegradable membranes are of great demand in modern technology. Similar membranes have been developed by irradiating different weight poly (vinyl alcohol) (PVA) – hydroxypropyl guar gum (HPG) blends and followed by combining with ex situ nanosilica. Polarized light microscopic (PLM) study indicates that electron beam irradiation produced crosslinks and develop...

Edible films were made from proteins (corn-zein and wheat gluten) and celluloses (methyl cellulose and hydroxypropyl cellulose), and tested fog permeability of gases. Oxygen and carbon dioxide permeabilities of edible films were generally lower than those of plastic films. However, water vapor permeabilities of edible films were higher than those of plastic films. The concentration of plasticiz...