Background and Aim: Preparation of root canal with rotary nickel-titanium (NiTi) instruments may potentially create microcracks that can lead to vertical root fracture. This study aimed to compare the incidence of crack formation by BioRaCe and Edge Taper Platinum systems in the mesiobuccal canals of extracted first mandibular molars. Materials and Methods: In this experimental study, 50 first...

∗To whom correspondence should be addressed †Chemical Engineering Department, Delft University of Technology, Julianalaan 136, 2628 BL Delft, The Netherlands ‡Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands ¶Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford, Cambridge, Massachusetts, 02138, USA; and Kavli Ins...

The cathodic dissolution of platinum, resulting from the oxygen reduction reaction (ORR) or hydrogen peroxide reduction on platinum, has been investigated. Highly oxidizing hydroxyl radicals (OH•) are believed to be the species responsible for the platinum dissolution phenomenon. These radicals are produced from the ORR byproduct, hydrogen peroxide, through a 1 electron reduction pathway (H2O2 ...

Although ovarian carcinomas with mutated BRCA1 or BRCA2 are sensitive to platinum compounds, such carcinomas eventually develop platinum resistance. Previously, we showed that acquired resistance to cisplatin in BRCA2-mutated tumors can be mediated by secondary intragenic mutations in BRCA2 that restore the wild-type BRCA2 reading frame. Here, we show that secondary mutations of BRCA1 also occu...

Abstract Metal–graphene–metal (M–G–M) stacks have provided new specific methods for the integration of two-dimensional (2D) materials into three-dimensional (3D) electronic devices, such as transistors, supercapacitors, memristors and others. Intentional control local properties in is primary problem to be solved when developing hybrid structures with 2D 3D elements. In order do this, physical ...

The electrocatalysts utilized as the prospective electrodes in fuel cells and high efficient energy conversion devices require both the interconnected channels for efficient electrolyte transportation and the superior catalytic activity with long service life. In this work, nanoporous gold with the rigid skeletons in three dimensions is partially decorated by porous platinum shell containing na...

Platinum-based catalysts have been considered the most effective electrocatalysts for the hydrogen evolution reaction in water splitting. However, platinum utilization in these electrocatalysts is extremely low, as the active sites are only located on the surface of the catalyst particles. Downsizing catalyst nanoparticles to single atoms is highly desirable to maximize their efficiency by util...

c/s-Diammine-1,1-cyclobutane dicarboxylate platinum(ll) (CBDCA, JM8) is a nonnephrotoxic analogue of cisplatin cur rently undergoing clinical evaluation. Pharmacokinetic studies have been performed in patients receiving CBDCA (20 to 520 mg/sq m) as a 1-hr infusion without hydration or diuresis. Follow ing the end of the infusion, plasma levels of total platinum and ultrafilterable (M, < 50,000)...