BACKGROUND Dysmenorrhea is one of the most common types of cyclic pain that affects 50% of women and girls in their menstrual ages. Because of the side-effects and contraindications of chemical medicines, using herbs has been investigated in treating dysmenorrhea. OBJECTIVES The aim of this study was to determine the effect of Rosa damascena extract on primary dysmenorrhea among the students ...

abstract background: different therapeutic methods have been applied for the treatment of dysmenorrhea and the method with the lesser side effects is preferred. the aim of this study was to compare the effects of herbal products (fennelin and vitagnus) and mefenamic acid in the treatment of primary dysmenorrhea. materials and methods: this double-blind clinical trial was carried out in 105 stud...

Purpose Primary dysmenorrhea (PD) is a common cause of pelvic pain that can cause limitations in daily activities. Treatment options sometimes result in failure, suggesting that different mechanisms may be effective in etiopathogenesis. Eosinophils are cells that are present in endometrium only in the perimenstrual period. The aim of this study was to evaluate the levels of eotaxin, a potent eo...

This meta-analysis aimed to evaluate the effectiveness of acupuncture or acupressure at the Sanyinjiao (SP6) acupoint in relieving pain associated with primary dysmenorrhea. We searched the scientific literature databases to identify randomized controlled trials. The primary outcome was visual analogue scale (VAS) pain score. Three acupuncture and four acupressure trials were included in the me...

Background: Dysmenorrhea is a painful syndrome that accompanies the menstrual cycles. Although exercise is generally though to alleviate the dysmenorrhea, the scientific literature display mixed evidence. The main objective of this research was to determine the effects of exercise on primary dysmenorrhea. Methods: This study was a randomized clinical trial of 150 high school girl students in Ma...

Primary dysmenorrhea is one of the most common gynecological complaints in young women, but potential peripheral immunologic features underlying this condition remain undefined. In this paper, we compared 84 common cytokine gene expression profiles of peripheral blood mononuclear cells (PBMCs) from six primary dysmenorrheic young women and three unaffected controls on the seventh day before (se...

BACKGROUND DLBS1442, a proprietary and standardized semipolar bioactive extract of the fruit Phaleria macrocarpa, is preclinically proven to have anti-inflammatory properties. The current clinical study evaluated the efficacy and safety of DLBS1442 in alleviating symptoms of premenstrual syndrome and primary dysmenorrhea. METHODS This was an open study over four menstrual cycles (with two con...

conclusions wheat germ extract seems to be an effective treatment for dysmenorrhea and its systemic symptoms, probably because of its anti-inflammatory effects. results pain severity decreased only in the wheat germ extract group (p < 0.001) and there was no statistically significant change in the placebo group. in the wheat germ extract group, the pain severity decreased from 4.701 at baseline...