Activation and inactivation of voltage-gated sodium channels are critical for proper electrical signaling in excitable cells. Pyrethroid insecticides promote activation and inhibit inactivation of sodium channels, resulting in prolonged opening of sodium channels. They preferably bind to the open state of the sodium channel by interacting with two distinct receptor sites, pyrethroid receptor si...

Pyrethroids are widely used insecticides that may seriously harm aquatic organisms. Being strongly hydrophobic, pyrethroids in solution occur only in short pulses but may be retained in sediments for longer periods. Consequently, most studies consider the chronic exposure of sediment dwelling organisms. We collected data from 16 studies to determine effect thresholds for stream macroinvertebrat...

The possible association between maternal exposure to pyrethroid insecticides (PYRs) during pregnancy and infant development was explored. Levels of exposure to PYRs was assessed by metabolite (3-phenoybenzoic acid, 3-PBA) concentration in maternal spot urine sampled in the first trimester of index pregnancy, and infant development was assessed at 18 months of age using the Kinder Infants Devel...

Aquatic exposure arising from the use of pyrethroid insecticides on cotton in the United States was estimated as part of an extensive pyrethroid aquatic risk assessment. The exposure analysis was based on the standard U.S. Environmental Protection Agency tier II regulatory scenario for cotton, which assumes a 1-ha pond surrounded by 10 ha of treated crop, with high levels of runoff, erosion, an...

background: the german cockroach, blattella germanica (l), is a world wide hygienic pest that is very difficult to control. extensive usage of insecticides may develop resistance to a variety of insecticides, causing failure to control. this study was designed to determine resistance of hospital-collected strains of the german cockroach to carbamate and organophosphorous insecticides. methods: ...

Cochliomyia hominivorax larvae are known for their parasitic habit in living vertebrates, causing considerable economic losses to livestock industry. This ectoparasite has been controlled mainly by applying insecticides, but this method usually results in the selection of resistant individuals. The resistance mechanism known as knockdown resistance (kdr) is a generic term for amino acid substit...

Paresthesias have previously been reported among adults in occupational and non-occupational settings after dermal contact with pyrethroid insecticides. In this report, we describe a preverbal 13-month-old who presented to his primary care pediatrician with approximately 1 week of odd facial movements consistent with facial paresthesias. The symptoms coincided with a period of repeat indoor spr...

Abstract The objective of this study was to observe the response bird cherry oat aphid, Rhopalosiphum padi (Linnaeus, 1758) field rate equivalents insecticides, by using bioassays vials coated with pyrethroid, λ-cyhalothrin. results from geographically separated Irish R. colonies indicated a susceptible response, which similar finding UK showed sensitivity in species cereal aphids. Monitoring s...

background: we aimed to evaluate different fibres of bednets impregnated with various pyrethroids. the stability of insecticide on the bednet was measured using different methods of washings as well as local made detergents. methods: the entire test was carried out according to the who-recommended methods. in addition, the impact of the numbers of washes on the stability of the insecticides was...