نتایج جستجو برای: ras al
تعداد نتایج: 471474 فیلتر نتایج به سال:
Mental Health and Oral Health-Related Quality of Life in Patients with Recurrent Aphthous Stomatitis
Background and purpose: Recurrent aphthous stomatitis (RAS) is one of the most common oral mucosal diseases. The etiology of RAS is unknown, however, some factors are considered to be involved in its occurrence, including genetic factors, trauma, menstruation, stress, anxiety, etc. Mental disorders such as stress and anxiety play a key role in the onset and recurrence of RAS lesions. The purpo...
Several tumorigenic (benign and malignant) clones have been raised from the human epidermal cell line HaCaT after transfection with the c-Ha-ras oncogene (val 12) (P. Boukamp et al., Cancer Res., 50: 2840-2847, 1990). In culture, these HaCaT-ras clones expressed epidermal differentiation markers, such as keratins K1 and 10, at high density or upon depletion of retinoic acid. Accordingly, as HaC...
Activated ras oncogene transfection into suitable recipient cells has been shown to induce the metastatic phenotype (Thorgeirsson, et al., Mol. Cell. Biol., 5: 259-262, 1985). We have used this model system to study the correlation of basement membrane collagenolysis with metastatic propensity. The c-Ha-ras oncogene alone, or combined with v-myc, transfected into early passage rat embryo fibrob...
S. Barannikova, L. Zuev, Institute of Strength Physics and Materials Science of Siberian Branch Russian Academy of Sciences (ISPMS SB RAS) and National Research Tomsk State University «TSU» ; A. Bochkareva, A. Lunev, ISPMS SB RAS and National Research Tomsk Polytechnic University «TPU»; Yu. Li, ISPMS SB RAS; G. Shlyakhova, ISPMS SB RAS and Seversk Technological Institute branch of State Autonom...
Background and objectives: Recurrent aphthous stomatitis (RAS) is a painful ulcerative lesion and its incidence is 20% in the society. Myrtus communis (myrtex) has been effective in the treatment of RAS. In this study, two different concentrations (2.5% versus 5%) of myrtex extract were evaluated to discover the most effective concentration for the treatment of RAS. Methods: In this randomized...
p53 is the most frequent target for genetic alterations in a wide variety of human cancers. The product of the p53 tumor suppressor gene binds to DNA and activates transcription from promoters containing its consensus binding site. In the accompanying paper we have found that P53 tumor suppressor protein recognizes specifically a transcriptional element within the human H-ras protooncogene (Spa...
Background and Aims: Recurrent aphthous stomatitis (RAS) is the most common oral mucosal inflammatory disease. The frequency of RAS is as much as 20% in the general population. The cause of RAS is not yet fully understood. Antioxidant is a material which has ability to preserve molecules from damage and also can delay the start of it. The aim of this study was to compare saliva level of total a...
Background and purpose: Metadiscourse markers (MDMs) play a significant role in academic witting. They act as a bridge between writers and readers and make a text more understandable. Therefore, this study aimed at investigating the use of MDMs in introduction, methods, results, and discussion (IMRaD) sections of English medical research articles (RAs) published in Iranian and American ISI jour...
The guanine nucleotide binding protein Ras plays a central role as molecular switch in cellular signal transduction. Ras cycles between a GDP-bound "off" state and a GTP-bound "on" state. Specific oncogenic mutations in the Ras protein are found in up to 30% of all human tumors. Previous 31P NMR studies had demonstrated that in liquid solution different conformational states in the GDP-bound as...
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