background: induction chemotherapy for acute lymphoblastic leukemia achieves complete remis sion in over 90% of children. it is apparent therefore that many patients in clinical remission and with out residual disease detectable by conventional light microscopy of peripheral blood or bone marrow films still harbor viable cells of the original disease mrd analysis does have a useful role to play...

Short bowel syndrome (SBS) occurs when, after surgery or congenitally, a patient is left with 200 cm of functional small intestine. Absorption is related to the amount of residual intestine; patients at greatest nutritional risk generally have a duodenostomy or a jejunoileal anastomosis with 35 cm of residual small intestine, jejunocolic or ileocolic anastomosis with 60 cm of residual small int...

We consider the hedging problem in a jump-diffusion market with correlated assets. For this purpose, we employ the locally risk-minimizing approach and obtain the hedging portfolio as a solution of a multidimensional system of linear equations. ‎This system shows that in a continuous market, independence and correlation assumptions of assets lead to the same locally risk-minimizing portfolio. ‎...

Many software projects are inevitably associated with various types and degrees of uncertainty. It is not uncommon to see software project spiral out of control with escalated resource requirements. Thus, risk management techniques are critical issues to information system researchers. Previous empirical studies of US software firms support the adoption of development standardization and user r...

The part of credit spread that is not explained by corporate credit risk forecasts future economic activity. I show that the link with aggregate business risk and bond liquidity risk explains this finding. Once I project spreads on these two risk factors, which are readily measurable with the daily frequency, in addition to corporate credit risk, the forecasting power of the residual spread red...

Risk of coronary heart disease over 14 years was examined prospectively in 2,282 men and 2,845 women according to their antecedent cholesterol and lipoprotein status. An increased risk proportional to antecedent serum cholesterol was found whether or not it was associated with elevated S,20 400 prebeta lipoprotein. When adjustment was made for the concomitant prebeta lipoprotein concentration a...

INTRODUCTION While a positive margin after an attempt at breast conservation therapy (BCT) is a reason for concern, there is more controversy regarding close margins. When re-excisions are performed, there is often no residual disease in the new specimen, calling into question the need for the procedure. We sought to examine the incidence of residual disease after re-excision for close margins ...

PURPOSE We report on our experience with the Memotherm stent implanted in high-risk patients who had an indwelling catheter. PATIENTS AND METHODS Seventeen patients (mean age 80.6 years, range 55 to 93) who had an indwelling catheter were treated by placement of the Memotherm stent. The mean duration time of indwelling catheter were 12.7 months (range 1 to 60). The methods of implantation was...

The management of pure ductal carcinoma in situ (DCIS) involves local excision, with or without consecutive radiotherapy, or simple mastectomy. Assessment of the recurrence risk is the essential step in decision-making. The hypothesis of this study was that besides the apparition of true recurrences after prior complete excision there may be also cases with residual disease present distant from...