The treatment of multidrug-resistant (MDR), extensively drug-resistant or pandrug-resistant non-fermenting Gram-negative bacterial infections constitutes a challenge in an era of few new antibiotic choices. This mandates the re-evaluation of already existing antibiotics such as fosfomycin. We systematically reviewed the literature to assess the clinical and microbiological effectiveness of fosf...

background and objective: uttarakhand region is less explored, but possess a great biodiversity. this diversity can be explored for isolation and characterization of new actinomycetes strains for seeking antimicrobial molecules. it can therefore be predicted that novel bioactive metabolite producing actinomycetes can be discovered to combat multidrug resistant bacterial pathogens. materials and...

In modern medical processes, new antimicrobial drugs are being widely used in order to rapid and essential eradication of resistant bacterial strains. Broad-spectrum beta-lactamases are enzymes originated from mutations in the common plasmid genes mediators for beta-lactamases such as TEM-1, TEM-2, and SHV-1 are transferred among bacterial species. The genes coding the production of ESBL are of...

background: in this study, we determine the vector competence of musca domestica with reference to the transmis­sion of susceptible and resistance bacterial strains in hospitals and slaughter house in sanandaj city, west iran. methods: totally 908 houseflies were collected to isolate bacteria from their external body based on standard proce­dures.antibiotic susceptibility testing was performed ...

Emerging multidrug resistant bacterial infections are burning public health concerns worldwide. There is an urgent need to explore alternative antimicrobial agents for effective management of bacterial infections. Garlic (Allium sativum) has been traditionally used for the treatment of different diseases since ancient times. The present study aims to evaluate the antimicrobial activity of aqueo...

Methicillin-sensitive and resistant Staphylococcus aureus (MSSA and MRSA, respectively) can cause non-tuberculosis infectious spondylitis. In 43 cases of bacterial infectious spondylitis, Mycobacterium tuberculosis and S. aureus were the two major causative pathogens. MRSA caused more anterior operations and thoracic infections, while MSSA caused more posterior infections and lumbar infections....

The existence of bacterial clones was evident in early phenotypic studies that recognised high levels of similarity in geographically and temporally separated isolates. Multilocus sequence typing (MLST) has become the most common method for genetically characterizing clones of several bacterial pathogens, allowing the tracking of hypervirulent/antibiotic-resistant lineages. MLST has also been u...

Emergence and distribution of multi-drug resistant (MDR) bacteria in environments pose a risk to human and animal health. A total of 82 isolates of Escherichia spp. were recovered from cloacal swabs of migrating and non-migrating wild birds. All bacterial isolates were identified and characterized morphologically and biochemically. 72% and 50% of isolates recovered from non-migrating and migrat...

background: infections caused by pseudomonas aeruginosa or acinetobacter baumannii are of greatest concern for hospitalized patients, particularly those in intensive care units (icus). the aims of this study were to investigate the prevalence of integrons and biofilm formation among p. aeruginosa and a. baumannii isolates collected from icu and non-icu inpatients. materials and methods: a total...