Purpose We present the first case in the literature of a patient with Kartagener syndrome and ocular findings of nonexudative age-related macular degeneration. Observations A 55-year-old woman with Kartagener syndrome and chronic angle closure glaucoma presented for evaluation of the retina. Optos ultra-widefield imaging of the fundus showed glaucomatous cupping, drusen, and retinal pigment e...

Plaques of hard exudate measuring 0-5 to 10 disc diameters, which occurred in 5 eyes of 4 patients with diabetic maculopathy, showed complete organisation in 8 to 18 months with the formation of scars measuring 0-2 to 0 5 disc diameters. The visual acuity was related to the size and situation of the scar within the fovea, and, when the foveola was involved by plaque formation, visual reduction ...

The extent of damage to the blood-retinal barrier, induced by cryoapplication on the sclera, was measured in adult pigmented rabbits by using a vitreous fluorophotometer. In eight isolated cryopexies. the intensity of each was equalized by stopping freez.ing exactly when a white spot started to appear in the fundus. and the blood-retinal barrier damage was repaired 7-10 days after the operation...

Trypsin digestion of retinal pigment epithelium is a technique that bares Bruch's membrane, to allow topographical examination by scanning electron microscopy. Twenty-five human eyes were examined. The zonula occludens of the pigment epithelium was clearly seen as a surface feature, but attachment plaques at the sides and base were not visible. The adhesion between the pigment epithelium and th...

PURPOSE [3H]docosahexaenoic (DHA) acid was followed through the retinal pigment epithelial cells and photoreceptors for up to 5 days after injection to specifically determine which membrane systems of the retinal pigment epithelial cells are used in the handling of [3H]DHA after shedding and phagocytosis of rod tips. METHODS Frogs (Rana pipiens) were injected with [3H]DHA in the dorsal lymph ...

Retinal light damage in dark-reared rats supplemented with ascorbic acid and exposed to multiple doses of intermittent light was studied and compared with damage in unsupplemented dark-reared and cyclic-light-reared rats. The extent of photoreceptor cell loss from intense light exposure was determined by whole-eye rhodopsin levels and retinal DNA measurements two weeks after light treatment. Tw...

The authors relate an uncommon case of combined hamartoma of the retina and retinal pigment epithelium associated with optic coloboma.