Osteoporosis has become a major medical problem as the aged population of the world rapidly grows. Osteoporosispredisposes patients to fracture, progressive spinal deformities, and stenosis, and is subject to be a major concernbefore performing spine surgery, especially with bone fusions and instrumentation. Osteoporosis has often beenconsidered a contraindication for spinal surgery, while in s...

Chordomas are rare tumors from primitive notochord. They are usually located at sacrococcygeal region when it affects the spine. We present a case of giant chordoma in the thoracolumbar spine in Peru. A 43-year-old woman came to the hospital in Huanuco due to back pain and sensorymotor alterations in the lower limbs. Imaging confirmed an unresectable tumor involving the spine. Two years later, ...

Synaptopodin is an actin-associated molecule essential for the formation of a spine apparatus in telencephalic spines. To study whether synaptopodin and the spine apparatus organelle are regulated under conditions of lesion-induced plasticity, synaptopodin and the spine apparatus were analyzed in granule cells of the rat fascia dentata following entorhinal denervation. Confocal microscopy was e...

Objective: Traumatic spine injuries are seriously important and are associated with considerable morbidity and mortality. The goal of this study is to determine the epidemiology of the traumatic spine injuries in Shahid Beheshti Hospital of Kashan University of Medical Sciences (KAUMS), the main trauma center in Kashan, Iran.Methods: This cross-sectional study was undertaken on all cases ...

It is the unique interaction between the solid and fluid components that provide the intervertebral discs the strength and flexibility necessary to bear the physiological loading of the spine. The current research is directed towards developing a numerical model of a lumbar disc including the fluid flow into and out of the intervertebral disc. The presence of the fluid is imperative in order to...

conclusions both dexmedetomidine and esmolol can be used as agents to control hypotension in patients undergoing lumbar spine decompression and fixation surgery; the dexmedetomidine group, however, was associated with better intraoperative hemodynamic stability and reduced intraoperative analgesic and volatile anaesthetic requirement. results the study results showed that dexmedetomidine had lo...

INTRODUCTION The follower load represents the path of the internal force resultant passing through the centers of rotation of successive spinal segments. An ideal follower load is perpendicular to the mid-plane of the intervertebral disc and minimizes shear and bending moments at all levels. Patwardhan and colleagues showed that a follower compressive preload increases the stability and load ca...

Over the past decade considerable emphasis has been placed on understanding the psycho-social aspects of low back pain. Prior to this great emphasis had been placed on pathological and mechanical factors associated with the development of low back pain. The shift away from this mechanical approach despite a growing body of valid scientific evidence in support of this approach has possibly led t...

BACKGROUND The interpretation of thoracic spine X-rays is difficult because these images cannot clearly visualize the thoracic spine because of the overlap with soft tissues, such as the heart and pulmonary blood vessels. Thus, to improve the clarity of thoracic spine radiographs using existing radiograph equipment, we have investigated a one-shot energy subtraction method to visualize thoracic...