نتایج جستجو برای: steroid cell tumor

تعداد نتایج: 1950746  

Journal: :cell journal 0

objective: micrornas (mirnas) are a new class of non-coding rnas involved in regulating various biological processes including proliferation, differentiation, and apoptosis, among others. alterations in mirna expression are reported in several human cancers, which suggests their potential roles in tumor initiation and progression. members of the mir-302 cluster are highly expressed in embryonic...

Journal: :cell journal 0

objective: there are several factors, like environmental agents, neurotrophic factors, serotonin and some hormones such as estrogen, affecting neurogenesis and neural differentiation. regarding to importance of proliferation and regeneration in central nervous system, and a progressive increase in neurodegenerative diseases, cell therapy is an attractive approach in neuroscience. the aim of the...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2005
Ingo B Runnebaum Ansgar Brüning

PURPOSE Almost all patients with epithelial ovarian cancer receive chemotherapy and, concurrently, the synthetic steroid hormone dexamethasone to alleviate the side effects. This study aims to test the impact of steroid hormones on the apoptosis of epithelial ovarian cancer cells and to identify its mediators. EXPERIMENTAL DESIGN Tumor cell lines from 19 patients with advanced epithelial ovar...

2016
Victor M. Zaydfudim Shawn J. Pelletier

The deleterious long-term side effects and metabolic complications of corticosteroids have inspired initial clinical investigation of corticosteroid withdrawal and avoidance protocols in liver transplantation. The original studies in the 1990s focused on the safety of steroid withdrawal in patients without hepato-cellular carcinoma (HCC). 1,2 Subsequent clinical trials suggested noninferiority ...

Journal: :Endoscopy international open 2016
Noboru Hanaoka Ryu Ishihara Noriya Uedo Yoji Takeuchi Koji Higashino Tomofumi Akasaka Takashi Kanesaka Noriko Matsuura Yasushi Yamasaki Kenta Hamada Hiroyasu Iishi

BACKGROUND Although steroid injection prevents stricture after esophageal endoscopic submucosal dissection (ESD), some patients require repeated sessions of endoscopic balloon dilation (EBD). We investigated the risk for refractory stricture despite the administration of steroid injections to prevent stricture in patients undergoing esophageal ESD. Refractory stricture was defined as the requir...

Gholamhossin Hassanshahi MalekHosein Asadi Mohammad Reza Mirzaei, Seyed Javad Mowla, Zahra Ahmadi,

Objective(s): The OCT4B1, as one of OCT4 variants, is expressed in cancer cell lines and tissues more than other variants and plays an important role in apoptosis and stress (heat shock protein) pathways. The present study was designed to determine the effects of OCT4B1 silencing on expressional profile of HSP40 gene family expression in three different human tumor cell lines. Materials and Met...

Germ cell tumors account for 2 to 3% of all cancers in children. These tumors appear in the testicles as painless masses. The primary treatment of these tumors is the removal of testicles and chemotherapy. Giant cell tumor of the tendon sheath (GCTTS) is slow-growing tumor and the primary treatment of this tumor is surgery and both surgery and radiotherapy in invasive type. This report presents...

Journal: :The Journal of biological chemistry 2014
Wei Zhao Cunjie Chang Yangyan Cui Xiaozhi Zhao Jun Yang Lan Shen Ji Zhou Zhibo Hou Zhen Zhang Changxiao Ye Donald Hasenmayer Robert Perkins Xiaojing Huang Xin Yao Like Yu Ruimin Huang Dianzheng Zhang Hongqian Guo Jun Yan

Cancer cell proliferation is a metabolically demanding process, requiring high glycolysis, which is known as "Warburg effect," to support anabolic growth. Steroid receptor coactivator-3 (SRC-3), a steroid receptor coactivator, is overexpressed and/or amplified in multiple cancer types, including non-steroid targeted cancers, such as urinary bladder cancer (UBC). However, whether SRC-3 regulates...

2006
Lola M. Reid Irwin Leav Paul W. L. Kwan Percy Russell Frederick B. Merk

We have established a transplantable tumor line, R198, de rived from a papillary (transitional cell) carcinoma of the human urinary bladder. In nude mice, the tumor line exhibits properties attributable to both prostatic and transitional epithelia. In tumorbearing animals given androgens, the neoplasm has a rapid growth rate, possesses low levels of measurable androgen receptors, produces tartr...

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