The main aim of the investigation was to explore a novel L-lactide-depsipeptide copolymer for the development of rivastigmine-loaded polymeric nanoparticles. L-lactide-depsipeptide synthesis was based on the ring opening polymerization reaction of L-lactide with the cyclodepsipeptide, cyclo(Glc-Leu), using tin 2-ethyl hexanoate as an initiator. Rivastigmine-loaded nanoparticles were prepared by...

Background: Curcumin as a yellow natural compound extracted from turmeric root is known it as an antibacterial agent. One of the nanoparticles ability is to decrease the defects of usual drug delivery systems. Chitosan is a low toxic, biodegradable, biocompatible and safe polymer which is used in production of nanoparticles. Nanoparticles like chitosan-tripolyphosphate (TPP) are able to increas...

A major barrier to drug and gene delivery is crossing the cell's plasma membrane. Physical forces applied to cells via electroporation, ultrasound and laser irradiation generate nanoscale holes in the plasma membrane for direct delivery of drugs into the cytoplasm. Inspired by previous work showing that laser excitation of carbon nanoparticles can drive the carbon-steam reaction to generate hig...

In this work the stability of TiN and TiC nanopowders in isopropyl alcohol as well as the fabrication of dense and well adhered thin coatings based on TiN and TiC by electrophoretic deposition (EPD) have been evaluated in terms of zeta potential and mass deposited when hydrazine is added. The surface of TiN and TiC nanoparticles has been modified to improve the dispersion in isopropyl alcohol a...

semi-aerobic leachate is characterized by organic matter (cod, bod) which is relatively low in concentration and difficult to biodegrade. in conventional treatment systems, the low biodegradability is attributed to partial stabilization of leachate at the landfill. biological treatment of leachate in malaysia is not well established and any important data for the treatment process is not availa...