AIMS The extent to which left ventricular (LV) mass, an independent cardiovascular risk factor, is determined by genetic factors is unclear. The aim of this study was to assess the heritability of LV mass and its association with three potential candidate genes. METHODS A population-based adult twin study model was utilized. Echocardiographic assessment of LV mass was performed in 110 twin pa...

The discovery and prioritization of heritable phenotypes is a computational challenge in a variety of settings, including neuroimaging genetics and analyses of the vast phenotypic repositories in electronic health record systems and population-based biobanks. Classical estimates of heritability require twin or pedigree data, which can be costly and difficult to acquire. Genome-wide complex trai...

PURPOSE To assess the heritability of anterior chamber depth (ACD) and relative anterior chamber depth (ACD/axial length, rACD) in Chinese in a classic twin study. METHODS Twins aged 7 to 15 years living in two local districts were recruited from the Guangzhou Twin Registry. Anterior chamber depth and axial length were measured by partial coherence laser interferometry. Zygosity in all same-s...

Considerable variability exists in patterns of brain aging within and across individuals. Quantifying familial contributions to brain structure in late life may help us understand this variability. We estimated heritability of gray and white matter volumes and cortical thickness in a sample of older adult full siblings (2-4 individuals per pedigree; N = 75). Estimation of heritability was based...

Selection of genotypes based on high value of heritability and forecasted genetic conditions would be an effective method for improvement of wheat cultivars. The present investigation was carried out to estimate the genetic variability of agro-physiological characters using biometrical genetic techniques in 20 bread wheat genotypes under irrigated condition. For this purpose an experiment was c...

Hybrids were produced by crossing female Caspian kutum Rutilus frisii kutum with male grass carp Ctenopharyngodon idella. The genome of eight larvae and parents were studied using microsatellite markers for genetic evaluation and verification. After DNA extraction from parent fish and progeny, hybrid heritability of two loci was assessed using two pairs of microsatellite primers. Hybridizie...

The main aim of this research was to estimate the genetic and phenotypic parameters for productive and reproductive traits of Esfahan native chickens. Traits included body weights at hatch (BW1), 8 weeks of age (BW8), 12 weeks of age (BW12), and at sexual maturity (WSM)], age at sex maturity (ASM), egg number (EN), average egg weight (AEW) in the first 12 weeks of production, and egg production...

Previous research identified that a review of the current industry New Zealand lamb survival trait was necessary as its recording accuracy was reliant on farmers notifying their Sheep Improvement Limited bureau of lamb deaths. This paper reports the decision rules and genetic parameters for a new lamb survival trait for the New Zealand sheep industry. These rules define the new lamb survival tr...

OBJECTIVE The Computerized Neurocognitive Battery (CNB) enables efficient neurocognitive assessment. The authors aimed to (a) estimate validity and reliability of the battery's Dutch translation, (b) investigate effects of age across cognitive domains, and (c) estimate heritability of the CNB tests. METHOD A population-representative sample of 1,140 participants (aged 10-86), mainly twin-fami...