The linear correlation between the EC50 values of 50 substances obtained in luminescence bioassays using Vibrio fischeri and Vibrio harveyi and in a fluorogenic bioassay using Escherichia coli was investigated. As a result, a significant correlation was found between the said values in all three toxicity tests. The bioassay using V. harveyi had a sensitivity similar to that of the fluorogenic b...

Background: This two-arm, randomized clinical study aimed to compare efficacy between topical Alpha ointment and topical hydrocortisone cream (1%) in the healing of radiation-induced dermatitis in breast cancer patients. Methods: The inclusion criteria comprised newly pathologically proven, locally advanced breast cancer (treated with modified radical mastectomy followed by sequential adjuvant ...

A wind tunnel bioassay system to screen mosquito repellents is described. A wind tunnel is utilized to exploit the upwind flight response of host-seeking mosquitoes. Mosquitoes within the wind tunnel are activated with human breath, fly upwind, and land on heated chick skins. This behavioral sequence results in a consistently high percentage of the test population approaching repellent or contr...

In 1983, the Radiation Protection Bureau of the federal Department of Health was formally recognized by the Canadian nuclear industry regulator, the Atomic Energy Control Board (AECB) as the National Calibration Reference Centre (NCRC, the Centre) for Bioassay and In Vivo Measurements. The Centre’s mandate was to provide practical reference standards to the AECB’s licensees for measurements the...

A statistical study of fitting log-normal distributions to air sampling concentrations and random intakes is reported in this paper. An improved method on the approximation of a sum of log-normal distributions to a log-normal distribution is used to forecast bioassay results and their uncertainties. These methods can be used in the design and implementation of air control monitoring and bioassa...

Taylor et al. (1993) described a pollutant bioassay based upon a change in the rate at which Gammarus pulex (L.) consumes a novel food source (eggs of the brine shrimp Anemia salina) when the animals are stressed by exposure to a pollutant. The bioassay is rapid and non-destructive, and produces results with less variation than reported using conventional leaf-feeding bioassays. However, it is ...

Some degree of error is inevitable in multi-agent bioassays regardless of design or measurement technology. Estimation error can be reduced post facto by exploiting the matrix partial ordering of the bioassay survival estimates. The standard method for this is order-restricted regression (ORR). If the joint action of the bioassay agents admits a tolerance-based interpretation, additional struct...

Summiary. Parameters of the bioassay based on the gibberellin-indluced reducing suigar release of barley endosperm were investigated. Procedures for the rapid handling and processing of utp to several hundred treatments witholut loss in sensitivity of the test are described, and the effects of variations in many aspects of the bioassay were assessed. In general, the variations in varieties, tec...