Human herpesvirus 8 (HHV8), also known as Kaposi’s sarcoma herpesvirus, causes Kaposi’s sarcoma (1) and is associated with body cavity-based lymphomas and multicentric Castleman’s disease (2,3). HHV8 is spread sexually (4,5), but other routes of transmission probably exist because, in some cases, infection has been shown to be acquired in childhood in HHV8-endemic areas, such as Mediterranean E...

Background: Hepatitis C virus (HCV) infection is the most common transfusion transmitted disease in poly-transfused patients worldwide. In this study we aimed to evaluate the effects of pegylated interferon alfa-2a (PEG-IFN A-2a) in reducing serum ALT and eradicating serum hepatitis C virus (HCV) RNA in HCV infected polytransfused thalassemic patients. Materials and Methods: A cohort of 51 HCV-...

introduction hepatitis b infection remains a major health problem worldwide and is an important cause of morbidity and mortality. since it is transmitted parenterally, investigation of new cases of hepatitis b infections for potential routes of transmission plays a crucial role in controlling hepatitis b infection in the community. case presentation in this study, we reported a new case of hepa...

BACKGROUND Blood transfusion has always been an important route for Chagas Disease (CD) transmission. The high prevalence of CD in Latin America and its lifelong asymptomatic clinical picture pose a threat for the safety of the blood supply. The outcome of measures designed to improve transfusion safety can be assessed by evaluating the prevalence of CD among multitransfused patients METHODS ...

Torque Teno virus (TTV) is a transfusion transmitted virus that seems to be involved in several complications such as acute respiratory diseases, liver diseases, AIDS, cancer, and autoimmune reactions. In the present study the frequency of TTV was investigated among β- thalassemia (BT) and haemodialysis (HD) patients (high risk patients for TTV) in Mazandaran province, Iran. DNA was extracted f...

Babesiosis is a potentially life-threatening zoonotic disease that is endemic to the northeastern United States and increasing in prevalence worldwide. Transmitted by the same Ixodes tick responsible for Lyme disease, the intraerythrocytic parasite Babesia causes a wide range of clinical presentations--from asymptomatic carriage to a fulminant course with rapid deterioration. Symptoms typically...

Background and Objective: Hepatitis A virus (HAV) and hepatitis E virus (HEV) are both transmitted by the fecal-oral route and are known as leading causes of acute viral hepatitis in the world, especially in developing countries. There is a lack of updated data on HAV and HEV seroprevalence in the north of Iran. This study aimed to determine the seroprevalence of HAV and HEV among blood donors ...

In 1983, a small textbook was published entitled Microbiology in Blood Transfusion (Barbara, 1983). At the beginning of this book the characteristics of microbial agents that might predispose them to the potential for transmission by transfusion were explored. Some of the characteristics identified included: Presence of the agent in one or more of the constituent components of blood Propensity ...

Institute of Medical Microbiology and Immunology mia during follow-up between 5 months and 4 years. The other 60 patients remained negative in GBV-C PCR. Department of General Surgery One important route of GBV-C transmission is blood products (blood Department of Internal Medicine plasma and erythrocyte and thrombocyte concentrates). Therefore, we Department of Transfusion Medicine examined th...