Cranberry juice is used routinely, especially among women and the elderly, to prevent and treat urinary tract infections. These individuals are likely to be taking medications concomitantly with cranberry juice, leading to concern about potential drug-dietary substance interactions, particularly in the intestine, which, along with the liver, is rich in expression of the prominent drug metaboliz...

Background: Tuberculosis is a global and serious Public Health problem due to the increase of multidrugresistant and extensively drug-resistant cases; as a result, diverse research groups worldwide are focusing their efforts on finding novel antituberculous agents that can provide greater effectiveness, less toxicity and having a specific mechanism of action, possibly being coadjuvants in the t...

Natural products derived from plants have been used for decades in traditional medicine. Many classes of compounds exist such as saponins, alkaloids, anti-oxidants, etc. Pentacyclic triterpenes are also one the occurring plants. In this class Ursolic acid is a well-recognized compound that available various sources like seeds well fruits and possess many types activities bright contender develo...

The study aimed to examine the effect of extracted and standard ursolic acid in addition hyperinsulinemia compared vitamin B complex on liver kidney function alloxan-induced diabetic male rabbits. functions were determined analyzed by one–way a NOVA at variance software P-Value 0.05. result showed significant decrease aspartate aminotransferase (AST), alanine (ALT), alkaline phosphatase (ALP), ...

A new acylated triterpene together with prunasin, (-)-epicatechin, daucosterol, and three triterpenes, ursolic, oleanolic, and pomolic acids was isolated from the root of Chaenomeles japonica (THUNB.) LINDL. (Rosaceae) and determined to be 3-O-(E)-3, 5-dihydroxycinnamoylursolic acid on the basis of NMR and FAB-MS experiments.

The title compound, C(34)H(54)O(5), was synthesized by the reaction of ursolic acid with ethyl chloro-acetate in the presence of DMA. All six-membered rings of the penta-cyclic triterpene skeleton adopt chair conformations. In the crystal structure, mol-ecules are linked by inter-molecular O-H⋯O hydrogen-bond inter-actions, forming zigzag chains along the c axis.