COVID-19 can affect multiple organs, including skin. A wide range of skin manifestations have been reported in literature. Six main phenotypes identified: i) urticarial rash, ii) confluent erythematous/maculopapular/morbilliform iii) papulovesicular exanthem, iv) a chilblain-like acral pattern, v) livedo reticularis/racemosa-like and vi) purpuric vasculitic pattern. The pathogenetic mechanism i...

Zusammenfassung Das familiäre Mittelmeerfieber (FMF) ist die häufigste autoinflammatorische Erkrankung und gehört zu den monogenetischen Fiebersyndromen. Die beruht auf einer Mutation des MEFV -Gens; dieses dem kurzen Arm von Chromosom 16 lokalisiert kodiert für das Protein Pyrin. Pyrin aktiviert über mehrere Schritte eine erhöhte Ausschüttung der proinflammatorischen Zytokine Interleukin (IL)‑...

Objective-To identify clinical consequences of acute human herpesvirus type 6 infection by hypothesising that the virus will induce similar clinical syndromes to cytomegalovirus. Design-Examination of consecutive serum samples from patients with illnesses compatible with acute cytomegalovirus infection or exanthem subitum by indirect immunofluorescence for the presence of antibodies to human he...

Seroprevalence of human herpesvirus 6 (HHV-6) and HHV-7 infections is very high throughout the world, and almost all people are exposed first to HHV-6 and second to HHV-7 in their childhood. However, it is not clear whether the neutralizing (NT) antibody response between each virus is cross-reactive or not. To elucidate the NT antibody response between each virus, 55 serum samples from an adult...

aim : the aim of this study was to identify and compare the pattern of acute viral hepatitis in two regions of iran. background : the epidemiological pattern of acute hepatitis varies across the globe depending on geographic region, health status, socioeconomic conditions and differences in exposure to etiological factors. patients and methods : a cross-sectional study was carried out among 357...

measles is one of the viral and extremely contagious and acute diseases of childhood affecting almost all children. prior to the discovery of the measles vaccine, the mortality from this disease was one of the highest child mortality figures, especially in the developing countries, with the death rate ranging over 5 to 10% of the infected? before the vaccination program i was launched in the co...

context several risk factors play the role in the development of hepatocellular carcinoma (hcc) from which chronic hepatitis b and c infections are the most important ones. dna integration of hepatitis viruses alters the function of critical genes promoting malignant transformation of virus-infected liver cells. evidence acquisition there are remarkable geographic differences in prevalence of c...