dear editor-in-chief   lesional histopathological features in pityriasis rosea (pr) are non-specific (1).  our aim here is to investigate whether a histopathological take-off sign (tos) is associated with pr.

Asymmetric periflexural exanthem (APE) is a distinctive exanthem, probably viral in origin. It is largely a disease of childhood and is uncommon in adults. We report an adult man presenting with the typical clinical findings of APE.

Unilateral laterothoracic exanthem (ULE) (also termed asymmetric periflexural exanthem of childhood APEC) has been linked to viral infection, in particular parvovirus B-19, citomegalovirus and Ebstein Barr virus. Its prevalence is higher during spring and winter, most published reports involve white people. The diagnosis is clinical, the virusological tests, in most of the cases, are negative. ...

IMPORTANCE Recognition of different clinical presentations of viral and virally triggered ("paraviral") exanthems is necessary for patients to be appropriately diagnosed and counseled. OBSERVATIONS Nine children presented with eruptions of hypopigmented macules following coryzal symptoms. Other diagnostic considerations, such as pityriasis alba, pityriasis versicolor, and progressive macular ...

After an absence of ≈200 years, chikungunya returned to the American tropics in 2013. The virus is maintained in a complex African zoonotic cycle but escapes into an urban cycle at 40- to 50-year intervals, causing global pandemics. In 1823, classical chikungunya, a viral exanthem in humans, occurred on Zanzibar, and in 1827, it arrived in the Caribbean and spread to North and South America. In...