Morphological and quantitative neutrophil abnormalities are common in the megaloblastic anemias of vitamin B12 and folic acid deficiency. Little is known, however, about the role of these vitamins in normal leukocyte function. Seven patients with megaloblastic bone marrows, four with vitamin B12 deficiency and three with folic acid deficiency, were studied to determine the effect, if any, of th...

Two elderly patients with vitamin B12 deficiency were found to have low immunoglobulin levels. These returned to normal on treatment with vitamin B12.

ABSTRACT Sleeve gastrectomy has increased in popularity over the last five years and it is likely to supersede gastric banding. Nevertheless, it is unclear whether vitamin B12 supplementation is required after surgery. The aim of this short report is to identify any vitamin B12 deficiency and highlight the necessity of post laparoscopic sleeve gastrectomy vitamin B12 monitoring. PATIENTS AND ...

BACKGROUND Folate and vitamin B12 are essential nutrients, whose deficiencies are considerable public health problems worldwide, affecting all age groups. Low levels of these vitamins have been associated with high concentrations of homocysteine (Hcy) and can lead to health complications. Several genetic polymorphisms affect the metabolism of these vitamins. The aims of this study were to asses...

A patient with recurrent pulmonary abscess, weight loss, and alcoholism was found to have extremely high serum vitamin B12 and unsaturated vitamin B12-binding capacity (UBBC) levels. While transcobalamin (TC) II was also increased, most of his UBBC was due to an abnormal binding protein which carried greater than 80% of the endogenous vitamin B12 and was not found in his saliva, granulocytes, o...

BACKGROUND The purpose of this study was to compare clinical features of vitamin B12 deficiency patients with a history of gastrectomy to those without a history of gastrectomy. METHODS Twenty-two patients with vitamin B12 deficiency were included. Patients' chief complaints, oral manifestations, blood examination results, and past medical histories were reviewed. RESULTS Eleven patients ha...

In developed countries, vitamin B12 (cobalamin) deficiency usually occurs in children, exclusively breastfed ones whose mothers are vegetarian, causing low body stores of vitamin B12. The haematologic manifestation of vitamin B12 deficiency is pernicious anaemia. It is a megaloblastic anaemia with high mean corpuscular volume and typical morphological features, such as hyperlobulation of the nu...

Long standing infection of Helicobacter pylori leads to atrophic gastritis most of the times. Atrophic gastritis most commonly causes Vitamin B12 deficiency. We report a case of atrophic gastritis in a young male in whom no vitamin B12 deficiency was seen.

Chapter IIntroduction Introduction........................................................... 3 Epidemiology and Transmition.................................... 5 H.pylori virulence.....................................................8 Gastro duodenal pathology and immunity............................14 Vitamin B12 deficiency and Pernicious Anemia.................17 Pernicious Anemia..............

Aim and Objective: To study the effects of Vitamin B12 deficiency in infants and to see if there were any changes in the findings on treatment on follow up scans. Materials &Methods: We present three cases, children of age 6, 9 and 12 months of age, whose mothers had vitamin B12 deficiency. Patients underwent MRI brain scans after taking proper consent and were followed up after they were treat...