نتایج جستجو برای: vitamin b12 deficiency

تعداد نتایج: 218900  

Vitamin B12 (cobalamin) is an essential coenzyme for nucleic acid synthesis. Animal protein is the major dietary source of vitamin B12. Deficiency of vitamin B12 leads to megaloblastic anemia, degeneration of the brain, spinal cord, peripheral nerves, and abnormalities of epithelial tissues. Two factors are necessary for the cure of megaloblastic anemia: one in food (extrinsic factor) and one i...

Journal: :international journal of pediatrics 0
gian maria pacifici via san andrea 32, 56127 pisa

vitamin b12 (cobalamin) is an essential coenzyme for nucleic acid synthesis. animal protein is the major dietary source of vitamin b12. deficiency of vitamin b12 leads to megaloblastic anemia, degeneration of the brain, spinal cord, peripheral nerves, and abnormalities of epithelial tissues. two factors are necessary for the cure of megaloblastic anemia: one in food (extrinsic factor) and one i...

Journal: :Age and ageing 2004
Robert Clarke J Grimley Evans J Schneede E Nexo C Bates A Fletcher A Prentice C Johnston P M Ueland H Refsum P Sherliker J Birks G Whitlock E Breeze J M Scott

OBJECTIVES to examine the prevalence of vitamin B12 deficiency and folate deficiency in later life in representative samples of the elderly population in the United Kingdom. DESIGN a population-based cross-sectional analysis of 3,511 people aged 65 years or older from three studies was used to estimate the age-specific prevalence of vitamin B12 deficiency and of folate deficiency. Vitamin B12...

Journal: :Haematologica 2006
Anne-Mette Hvas Hora Buhl Niels Bech Laursen Birger Hesse Lars Berglund Ebba Nexo

We report on the use of recombinant human intrinsic factor (rhIF) in a new vitamin B12 absorption test. Holotranscobalamin (holoTC) was measured before and 24 hours after intake of three 9-mg doses of vitamin B12 (B12) and again 24 hours after intake of the same dose of B12 together with rhIF (rhIF-B12). Nine patients with evident vitamin B12 deficiency had a significantly higher increase in ho...

Journal: :The Australasian medical journal 2014
Palaniyandi Anitha Rajendraprasad Sasitharan Thalavaisundaram Thambarasi Prabaharan Krithika Madhuvanthi Mohan Paramasivam Venkataraman Saji James Ponnurangam Nagarajan Vinoth

Deficiency of vitamin B12 (cobalamin) is a well-known cause of megaloblastic anaemia. It is a reversible cause of bone marrow failure and demyelinating nervous system disorder, hence early detection and prompt treatment of vitamin B12 deficiency is essential. After diagnosing vitamin B12 deficiency, tracking down its root cause is important in individualising the treatment approach. Helicobacte...

Journal: :international journal of preventive medicine 0
mohamad reza najafi vahid shaygannajad maryam mirpourian ali gholamrezaei

background: vitamin b12 (cobalamin) deficiency can result in some clinical and paraclinical characteristics similar to what is seen in multiple sclerosis (ms) patients. this study aimed to evaluate the controversial association between vitamin b12 deficiency and ms. methods: we measured serum vitamin b12 in 60 patients with ms and 38 healthy controls. clinical disability was evaluated according...

2014
Shaonong Dang Hong Yan Lingxia Zeng Quanli Wang Qiang Li Shengbin Xiao Xiaojing Fan

OBJECTIVE To assess the status of the vitamin B12 and folate of Chinese women living in northwest China. METHODS A population-based cross-sectional study was conducted in 2008 among Chinese women aged 10-49 years living in Shaanxi province of northwest China. A stratified multistage random sampling method was adopted to obtain a sample of 1170 women. The women were interviewed for collection ...

Journal: :Clinical chemistry 2006
Joshua W Miller Marjorie G Garrod Alan L Rockwood Mark M Kushnir Lindsay H Allen Mary N Haan Ralph Green

BACKGROUND The standard screening test for vitamin B12 deficiency, measurement of total plasma vitamin B12, has limitations of sensitivity and specificity. Plasma vitamin B12 bound to transcobalamin (holoTC) is the fraction of total vitamin B12 available for tissue uptake and therefore has been proposed as a potentially useful alternative indicator of vitamin B12 status. METHODS We compared t...

Journal: :iranian red crescent medical journal 0
niloofar khodabandehloo department of internal medicine, tehran university of medical sciences, tehran, ir iran masoud vakili department of hematology and oncology, tehran university of medical sciences, tehran, ir iran zahra hashemian department of pediatrics, hematology, oncology and genetics research center, shahid sadoughi university of medical sciences, yazd, ir iran; department of pediatrics, hematology, oncology and genetics research center, shahid sadoughi university of medical sciences, yazd, ir iran, tel: +98-3518224000, fax: +98-3518224100 hadi zare zardini department of pediatrics, hematology, oncology and genetics research center, shahid sadoughi university of medical sciences, yazd, ir iran; young researchers and elite club, yazd branch, islamic azad university, yazd, ir iran

objectives we assessed functional vitamin b12 deficiency in tehranian elderly admitted to elderly research center, university of social welfare and rehabilitation sciences. conclusions the prevalence of b12 deficiency was higher in this study compared to other studies, so more attention and massive efficacious policy should be designed to reduce the deficiency of this vitamin. results cut-off o...

Journal: :Hong Kong medical journal = Xianggang yi xue za zhi 2015
C W Wong

Vitamin B12 deficiency is common among the elderly. Elderly people are particularly at risk of vitamin B12 deficiency because of the high prevalence of atrophic gastritis-associated food-cobalamin (vitamin B12) malabsorption, and the increasing prevalence of pernicious anaemia with advancing age. The deficiency most often goes unrecognised because the clinical manifestations are highly variable...

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