To the Editor The publication of the article of Enriquez et al 1 coincided with the final steps of our study on the expression of CDX2 in normal and neoplastic follicular-derived cells of the human thyroid gland. Enriquez et al 1 evaluated CDX2 expression in 11 cases of columnar cell variant (CCV) of papillary thyroid carcinoma (PTC) and in thyroid tissue microarrays (TMAs) composed of normal t...

Mapping and comparing biodiversity in space is a routine task ecological research. However, accurate mapping requires exact distributional information as inputs. When geographical coordinate missing or when only coarse distribution of species available at the quadrat plot level, how can we effectively infer compare spatial patterns with reasonable accuracy while controlling confounding impacts ...

Mechanisms of clathrindependent endocytosis Although clathrin-mediated internalization has been investigated for many years, new technologies keep providing us with novel insights into its underlying mechanisms, with an unprecedented scale down to molecular details regarding the structure and dynamics of the proteins involved. The plasticity of clathrin-mediated internalization was well illustr...

This dissertation presents two statistical methodologies developed on multi-order Markov models. First, we introduce an alignment-free sequence comparison method, which represents a sequence using a multi-order transition matrix (MTM). The MTM contains information of multi-order dependencies and provides a comprehensive representation of the heterogeneous composition within a sequence. Based on...

RESUME : Le présent travail s’inscrit dans un processus d’amélioration continue de la fonction maintenance des entreprises industrielles. L’objectif recherché dans cette communication est de définir une nouvelle approche de mesure de performance de la fonction maintenance au niveau stratégique de l’entreprise. Cette approche constituera pour le manager un outil qui lui permettra d’identifier le...