AIMS Antecedent blood pressure (BP) may contribute to cardiovascular disease (CVD) independent of current BP. Blood pressure is associated with left ventricular mass index (LVMI) which independently predicts CVD. We investigated the relationship between midlife BP from age 36 to 64 and LVMI at 60-64 years. METHODS AND RESULTS A total of 1653 participants in the British 1946 Birth Cohort under...

BACKGROUND AND OBJECTIVES Ambulatory BP monitoring (ABPM) allows a better risk stratification than office BP in hypertensive patients. However, the clinical relevance of ABPM has not been extensively investigated in the CKD population. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Within the Chronic Kidney Disease Japan Cohort study, 2977 patients enrolled (62% men, aged 60.8±11.6 years) and ...

mycoplasma synoviae expressed variable lipoprotein haemagglutinin (vlha) is believed to play a major role in pathogenesis of the disease by mediating adherence and immune evasion. the aim of this study was sequencing iranian m. synoviae isolates for the detection of nucleotide variation in the m. synoviae vlha gene. using oligonucleotide primers complementary to the single-copy conserved 5´ end...

Two hundred cases of renal transplantation from living donors are reported from Shahid Hashemi Nejad Medical'Center in Iran. There were 127 male and 73 female patients with 67% in the third and fourth decade of life. All patients received grafts from living donors with 1 14 cases of HLA haploidentical, 55 cases of HLA identical matches and 24 unrelated donors. One year patient and graft su...

Renin-angiotensin-aldosterone system blockade has been shown to protect against renal damage in salt-supplemented, stroke-prone spontaneously hypertensive rats (SHRsp). Based on intermittent tail-cuff blood pressure (BP) measurements, it has been claimed that such protection is BP-independent and mediated by a blockade of the direct tissue-damaging effects of angiotensin and/or aldosterone. BP ...

The Gal/GalNAc-specific lectin on rat peritoneal macrophages (macrophage asialoglycoprotein binding protein, M-ASGP-BP) is structurally similar to rat hepatic asialoglycoprotein-binding protein (ASGP-BP) or rat hepatic lectin (RHL) and is highly homologous with the major component of RHL, RHL-1 (Ii, M, Kurata, H., Itoh, N., Yamashina, I., and Kawasaki, T. (1990) J. Biol. Chem. 265, 11295-11298)...

The transformation of mature (urbanized) phase the ancient Indus civilisation between ?4200 and 3800 years Before Present (yr BP) overlaps with beginning Meghalayan Age (?4200 ± 100 yr BP). Though exact cause(s) for decline urbanized are not yet clear, researchers continue to debate whether monsoonal dryness was sole cause or several other regional factors manifested in a compounding manner. He...