The aim of the study is to investigate anti-inflammatory property different parts Adansonia digitata (Malvaceae) extracts. A. an important medicinal plant West Africa including Ghana. used effectively in folk medicine treat inflammatory diseases such as joint disorders, asthma, toothache and painful swelling. Carrageenan-induced pedal oedema 7-day old chicks was model determine extracts obtaine...

Yukmijihwang-tang (YMJ; Liu wei di huang tang (China), Rokumigan (Japan)) has been used in the treatment of diseases including renal disorder, cognitive vitality, and diabetes mellitus. However, there is very little information regarding the toxicity of YMJ to give an assurance of safety for clinical treatment. To provide safety information for YMJ, we evaluated its acute and sub-chronic toxici...

ROS detoxification is an essential process in protecting plant cells and their organelles, which is caused by ROS generated in stress condition. Peroxidase (POD) isozyme, Malondialdehyde (MDA) content, and Ascorbate peroxidase (APX) activity are the indicators of plants for measuring pollution effects. The purpose of the present study was to investigate Cd-induced stress on POD isozymes, MDA co...

Objective: The objective of the present study was to evaluate the acute and sub-acute toxicity profile of ethanolic extracts of Punica granatum (L).whole fruit (EPWF) and seeds (EPS) and synthetic ellagic acid (EA) in Swiss albino mice following OECD guidelines. Methods: In acute toxicity study, mice were orally administered 2000 mg/kg body weight of extracts and synthetic compound. In subacute...

OBJECTIVES Low first-dose peak serum concentrations of amikacin and gentamicin are commonly reported in ICU patients. The present study aimed to assess whether 30 mg/kg amikacin or 8 mg/kg gentamicin achieved target concentrations in ICU patients with severe sepsis. PATIENTS AND METHODS Sixty-three ICU patients (Simplified Acute Physiology Score II = 43 ± 16) with severe sepsis and an indicat...

background: in nature, there are herbal extracts, while capable of reducing aflatoxin b1 in agricultural product by different mechanisms, may also act as growth promoters. objectives: in this study, aqueous extract of t. daenensis was evaluated to detoxify contaminated feed with aflatoxin b1 and to determine the effect of growth promoters in japanese quail. methods: to this purpose, at 24 d of ...

Alstonia scholaris has been used by traditional medicine practitioners since the medieval ages for the treatment of diseases. The aim of this research was to evaluate the acute and sub-acute oral toxicity of its methanolic extract. The acute toxicity test was conducted using Sprague Dawley (SD) rats. The methanolic extract of Alstonia scholaris stem bark (ASME) was administrated in a single dos...