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First-phase insulin response to intravenous glucose is impaired both in type 2 diabetic patients and in subjects at risk for the disease. Hyperglycemia can modify beta-cell response by either inhibiting or potentiating both first- and second-phase insulin release. In normal subjects, the effect of acute hyperglycemia on insulin secretion is controversial. We measured (in 13 healthy volunteers) ...
attempts have been made to study the thermodynamic behavior of 1,3 butadiene purification columns with the aim of retrofitting those columns to more energy efficient separation schemes. 1,3 butadiene is purified in two columns in series through being separated from methyl acetylene and 1,2 butadiene in the first and second column respectively. comparisons have been made among different therm...
Psoriasis and multiple sclerosis (MS) are physiologically distinct yet share genetic signals have overlapping pathogenesis. Previous studies suggest psoriasis patients at greater risk of MS than the general population, two diseases also comorbidities traits (for example, they both more prevalent in northern latitudes). To evaluate whether there is a direct causal relationship, we conducted Mend...
Among empirical disciplines, computer science and the engineering fields share the distinction of creating their own subject matter, raising questions about the kinds of knowledge they engender. The authors argue that knowledge acquisition in computer science fits models as diverse as those proposed by Piaget and Lakatos. However, contrary to natural science, the knowledge acquired by computer ...
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