Although cloning and expression of T-cell Receptors (TcRs) has been performed for almost two decades, these procedures are still challenging. For example, the use of T-cell clones that have undergone limited expansion as starting material to limit the loss of interesting TcRs, must be weighed against the introduction of mutations by excess PCR cycles. The recent interest in using specific TcRs ...

BACKGROUND Attention-deficit/hyperactivity disorder (ADHD) is the most commonly diagnosed mental disorder among children in the United States. While overall ADHD prevalence continues to rise, few have examined difference by race/ethnicity. OBJECTIVE To examine trends in parent-reported ADHD prevalence between 2003 and 2011 across racial/ethnic groups and the role of sociodemographic factors i...

In this chapter, we extend the techniques of Chapter 2.4 on Fano’s method (the local Fano method) to a more global construction. In particular, we show that, rather than constructing a local packing, choosing a scaling δ > 0, and then optimizing over this δ, it is actually, in many cases, possible to prove lower bounds on minimax error directly using packing and covering numbers (metric entropy...

Objectives: Nutrition-related practices and outcomes vary dramatically between athletes, traditional beliefs regarding the role of electrolytes hydration in exercise-associated muscle cramping (EAMC) may be hindering meaningful prevention strategies. The aim this study was to characterize carbohydrate (CHO), energy, exertion level, conjunction with electrolyte status assess these possible predi...

Accurate assessment of fruit and vegetable intakes is critical for cancer control research and public health surveillance. This report examines the bias and precision of two commonly used food frequency questionnaire methods to assess fruit and vegetable intakes: (a) the 5 A Day method, based on seven items; and (b) the summation method, based on adding total servings of all fruit and vegetable...

OBJECTIVES The aim of this study was to examine to what extent extreme endurance exercise results in changes of plasma markers associated with cardiac and renal damage, as well as hemolysis in male, Mexican Tarahumara runners. METHODS Ten Tarahumara runners (mean (sd) age of 38 (12) years) participated in a 78 km race in Chihuahua, Mexico at 2,400 m above sea level. Cardiac, kidney, and hemat...

ABSTRACT Genetic analysis for resistance to bacterial blight (Xanthomonas oryzae pv. oryzae) of 21 rice (Oryza sativa L.) cultivars was carried out. These cultivars were divided into two groups based on their reactions to Philippine races of bacterial blight. Cultivars of group 1 were resistant to race 1 and those of group 2 were susceptible to race 1 but resistant to race 2. All the cultivars ...

Anthracnose disease (Colletotrichum lindemuthianum (Sacc. et. Magn) Lams. Scrib.) is one of the most devastating diseases that constrain common bean production in Uganda. A cascading pedigree pyramiding scheme was used to develop populations evaluate effectiveness pyramided and single resistance genes (Co-42, Co-43, Co-5, Co-9) on development. Detached leaf trifoliates F4:6 genotypes were scree...