In recent years a great deal of new information has been obtained concerning the general haemodynamic changes that occur during attacks of angina pectoris. Most of the reports on this subject are based upon studies during exertional angina pectoris. Haemodynamic observations during spontaneous angina pectoris are more scanty, and recordings of cardiac output during spontaneous angina pectoris d...

Refractory angina pectoris is defined as angina refractory to optimal medical treatment and standard coronary revascularization procedures. Despite recent therapeutic advances, patients with refractory angina pectoris are not adequately treated. Spinal cord stimulation is a minimally invasive and reversible technique which utilizes electrical neuromodulation by means of an electrode implanted i...

BACKGROUND The purpose of this systematic review is to assess the effectiveness of acupuncture for angina pectoris. METHODS Eleven electronic databases were searched until January 2013. The study included randomized controlled trials that the effectiveness of acupuncture alone was compared to anti-angina medicines (in addition to conventional treatment) and the effectiveness of a combination ...

BACKGROUND Blood clotting activation is an important component of the inflammatory response; the outbursts of unstable angina are usually associated with increased thrombin formation and coronary mural thrombosis. METHODS AND RESULTS To investigate 1) whether monocyte activation is responsible for the enhanced thrombin formation during bursts of unstable angina and 2) what mechanism(s) might ...

Enhanced external counterpulsation (EECP) is a noninvasive circulatory assist device that has recently emerged as a treatment option for refractory angina in left ventricular (LV) dysfunction. This 2-year cohort study describes the long-term follow-up of patients who had severe LV dysfunction that was treated with EECP for angina pectoris and reports clinical outcomes, event-free survival rates...

Unstable angina is used interchangeably with a variety of other terms to refer to a clinical situation intermediate in severity between chronic effort angina and myocardial infarction. In most reports dealing with this syndrome, the patients were selected according to a number of criteria which varied from one study to another. Some authors recognized subgroups of patients with variable severit...

BACKGROUND Coronary artery spasm induces activation of the coagulation system. Turnover and maintenance of thrombus depend not only on formation but also on lysis. The relation between coronary spasm and fibrinolytic system has not been elucidated. OBJECTIVE To examine whether there is impairment of or a circadian variation in fibrinolytic activity in patients with variant angina. METHODS P...

Reported elevations of left ventricular filling pressures during angina suggest increased myocardial stiffness. Both left ventricular beginningand end-diastolic pressures and volumes were measured in seven patients before, during, and after angina induced by atrial pacing. During nine episodes of angina, mean end-diastolic pressure rose from 12 to 29 mm Hg and ejection fraction fell from 0.47 t...

Abstract Background There have been no cardiac biomarkers used in the diagnosis of unstable angina. In this study, we examined high sensitive troponin T and I as a marker to differentiate patients with angina from stable Methods A total 816 (59 AMI, 94 angina, 99 623 healthy individuals) were included. All had glomerular filtration rate ≥60 mL/min/1.73 m2. Leftover serum samples obtained who vi...