Bupropion is widely used for the treatment of depressive disorder and smoking cessation. Hyponatremia, including a syndrome of inappropriate secretion of antidiuretic hormone (SIADH), is not rare complication of treatment with antipsychotic drugs. We report a 60-year-old man who experienced severe hyponatremia after a treatment with bupropion for depressive disorder for the first time in the Ko...

The symptoms of chikungunya virus (CHIKV) infection include fever, headache, muscle aches, skin rash, and polyarthralgia, characterized by intense pain, edema, and temporary functional impairment. This is the first report of encephalitis caused by CHIKV infection associated with an atypical presentation of syndrome of inappropriate antidiuretic hormone secretion, evolving to cognitive impairmen...

Carbamazepine has recently been shown to have a vasopressin-like action and, like chlorpropamnide, to be effective in controlling polyuria in patients with diabetes insipidus (Hartman, 1972; Uhlich et al., 1972). In the case reported here carbamazepine, which was being given to a patient suffering from depression and psychogenic polydipsia, induced inappropriate secretion of antidiuretic hormon...

We describe the association of malignant thymoma with the syndrome of inappropriate antidiuretic hormone secretion and myasthenia gravis. Hyponatremia has not been reported associated with those tumors and our case should alert physicians about the potential for a life-threatening complication.

A 72-year-old woman with the syndrome of inappropriate secretion of antidiuretic hormone of unknown cause during more than one year of observation is reported. Plasma vasopressin levels were excessively elevated, even during a water load test. Her serum electrolyte abnormalities and general state were ameliorated after fluid restriction. During treatment with demeclocycline the patient was able...

A spontaneous intrapericardial haemorrhage caused cardiac tamponade in a 29 year old paraplegic man who was being treated with warfarin. The associated persistent hyponatraemia, which was believed to be caused by an inappropriately high release of antidiuretic hormone, rapidly resolved after pericardiocentesis.

We report a 45 year old man who presented with history suggestive of chronic meningitis. Laboratory investigations revealed lymphocytic meningitis and a syndrome of inappropriate antidiuretic hormone secretion. History, etiological workup and complications during hospitalization suggested the presence of both SLE and sarcoidosis. He improved with intravenous steroids and is doing well on follow...

Hyponatremia is the most frequently observed electrolyte abnormality in clinical practice, and its frequency is almost double in hospitalized cancer patients. As a subset of cancer, hyponatremia is quite common in lung cancer patients, and it is often coupled with the diagnosis of syndrome of inappropriate antidiuretic hormone secretion. The presence of hyponatremia is consequential in that its...