نتایج جستجو برای: antifungal drug resistance

تعداد نتایج: 927154  

2017
Ying Gong Tao Li Cuixiang Yu Shujuan Sun

In recent decades, the incidence of invasive fungal infections has increased notably. Candida albicans (C. albicans), a common opportunistic fungal pathogen that dwells on human mucosal surfaces, can cause fungal infections, especially in immunocompromised and high-risk surgical patients. In addition, the wide use of antifungal agents has likely contributed to resistance of C. albicans to tradi...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2011
David W Denning Steven Park Cornelia Lass-Florl Marcin G Fraczek Marie Kirwan Robin Gore Jaclyn Smith Ahmed Bueid Caroline B Moore Paul Bowyer David S Perlin

BACKGROUND Oral triazole therapy is well established for the treatment of invasive (IPA), allergic (ABPA), and chronic pulmonary (CPA) aspergillosis, and is often long-term. Triazole resistance rates are rising internationally. Microbiological diagnosis of aspergillosis is limited by poor culture yield, leading to uncertainty about the frequency of triazole resistance. METHODS Using an ultras...

Journal: :Medical mycology 2011
Susan Julie Howard Maiken Cavling Arendrup

Voriconazole is the recommended agent for invasive aspergillosis, with lipid amphotericin B or caspofungin as second line treatment choices. Being the only agents available in oral formulation, azoles are used in chronic infections and often over longer time periods. In addition to being used in clinical medicine, azoles are employed extensively in agriculture. Azole-resistant Aspergillus has b...

AdimiNaghan, Parvaneh, Rahimi, Mohammad Karim , Torkamani, Roya,

Background: Vaginal candidiasis is a common cause of vaginal infections. Currently, for treatment of these infections, fluconazole is prescribed more than other drugs; so determining the drug resistance of Candida to fluconazole and comparing it with itraconazole as a substitute has been one of the main objectives of this study. Materials and methods: Of 180 patients with symptoms of vaginal c...

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