The increasing problem of antibiotic resistance among pathogenic bacteria requires development of new antimicrobial agents. Synthesis and experimental application of the hybrids peptides may be one of the interesting possibilities in antimicrobial treatment. The aim of the present investigation is to determinate in vitro activities of two synthetic peptide amides: cecropin-melittin hybrid pepti...

The purpose of this study was to evaluate antibiotics effective for periodontopathic bacteria as chemotherapeutic agents for periodontal diseases. Antimicrobial activities of ten agents were evaluated by determinating minimal inhibitory concentrations against six periodontopathic bacterial species ( Bacteroides gingivalis, B. melaninogenicus ss intermedius, Fusobacterium nucleatum, Eikenella co...

ABSTRACT: Essential oils are commonly used to treat minor health problems. In this study the chemical compositions of Lavandula officinalis and Thymus vulgaris were determined by gas chromatography and mass spectrometry. GC/MS analysis of T. vulgaris resulted in thymol as the major oil component where as methyl sulfony exhibited as the most abundant constituent of L. officinalis. The antibacter...

background scrophularia striata (scrophulariaceae family) is an herbaceous plant that is traditionally used for treatment of microbial infections. objectives antimicrobial and antioxidant activity of different extracts (methanolic, ethanolic, aqueous and ethyl acetate) from s. striata aerial parts was evaluated. materials and methods the antimicrobial activity of different extracts from s. stri...

quantitative structure-activity relationship (qsar) studies of a series of substituted 3-hydroxy-pyridine-4-ones and 3-hydroxy-pyran-4-ones as antibacterial and antifungal agents against a variety of microorganisms were performed. multiple linear regression approach was used as variable selection method. the antimicrobial activities of these compounds against staphylococcus aureus, aspergilus n...

Objectives. Antimicrobial activities of non-thermal atmospheric plasma-treated liquids on various bacterial and fungal strains in their planktonic and biofilm forms have been widely reported. Since most of the plasmatreated liquids are water based, they might be washed off certain surfaces and they cannot be applied for the infections of respiratory tract. In the present study we have tested an...

The lipopolysaccharide binding domain (LBD) in anti-lipopolysaccharide factor (ALF) is the main functional element of ALF, which exhibits antimicrobial activities. Our previous studies show that the peptide LBDv, synthesized based on the modified sequence of LBD (named LBD2) from FcALF2, exhibited an apparently enhanced antimicrobial activity. To learn the prospect of LBDv application, the char...

Brown alga, Turbinaria conoides was successively extracted with n-hexane, cyclohexane, methanol and ethanol:water (1:1). The extracts were evaluated for antibacterial and antifungal activities by disc diffusion method. Minimal inhibitory concentration was determined for active extracts by broth dilution method. The antiviral activity and cytotoxicity of the extracts were tested in human embryon...