INTRODUCTION................................................................................................................. 89 Emergence of Multiresislant S. aureus.................................................................................... 89 Genetic Nature of Antimicrobial Resistance ...——....——......—.—......—..—..—.——.—..—.—...—. 90 TRANSFER OF RESISTANCE GENES IN STAPHYLOCOCCI......

Colibacillosis is a disease caused by Escherichia coli and remains major concern in poultry production, as it leads to significant economic losses due carcass condemnation clinical symptoms. The development of antimicrobial resistance growing problem worldwide concern. Lysogenic bacteriophages are effective vectors for acquiring disseminating antibiotic genes (ARGs). aim this study was investig...

To the Editor: In a letter recently published in Emerging Infectious Diseases, Smith (1) discussed evidence that he mistakenly believes to undermine the hypothesis that the fl orfenicol resistance gene present in some isolates of the epidemic Salmonella enterica serovar Typhimurium DT104 strain originated from a fl orfenicol resistance plasmid present in Vibrio damsela (Pasteurella piscicida) t...

The emergence of Clostridium difficile as a significant human diarrheal pathogen is associated with the production of highly transmissible spores and the acquisition of antimicrobial resistance genes (ARGs) and virulence factors. Unlike the hospital-associated C. difficile RT027 lineage, the community-associated C. difficile RT078 lineage is isolated from both humans and farm animals; however, ...

A total of 184 resistant Salmonella enterica isolated from poultry and swine were investigated for the distribution of and associations between various antimicrobial resistance genes. All the isolates were screened for the presence of class 2 and 3 integrase genes and 18 resistance genes corresponding to their resistance phenotypes. None of the isolates carried class 2 and 3 integrons. The inve...

colistin as therapy for nosocomial infections caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii. Contemporary assessment of antimicrobial susceptibility testing methods for polimyx-in B and colistin: review of available inter-pretative criteria and quality control guidelines. 9. National Committee for Clinical Laboratory Standards (NCCLS). Methods for dilution ant...

We characterized a multidrug-resistant (MDR) Enterobacter spp. isolate highlighting the genetic aspects of antimicrobial resistance genes. An (Ec61) was recovered in 2014 from transtracheal aspirate sample patient admitted to Brazilian tertiary hospital and submitted further microbiological genomic characterization.

Antimicrobial consumption is one of the major contributing factors facilitating the development and maintenance of bacteria exhibiting antimicrobial resistance. Plasmid-mediated quinolone resistance (PMQR) genes, such as the qnr family, can be horizontally transferred and contribute to reduced susceptibility to fluoroquinolones. We performed an observational study, investigating the copy number...

BACKGROUND Antimicrobial resistance is a major global health challenge. Metagenomics allows analyzing the presence and dynamics of "resistomes" (the ensemble of genes encoding antimicrobial resistance in a given microbiome) in disparate microbial ecosystems. However, the low sensitivity and specificity of available metagenomic methods preclude the detection of minority populations (often presen...