fluid invasion from water-based drilling mud (wbdm) into the shale formations causes swelling,high pressure zone near the wellbore wall, and eventually wellbore instability problems duringdrilling operations. for the stability of the wellbore, physical plugging of nanoscale pore throats couldbe considered as a logical approach toward avoiding the fluid invasion into the shale formation. thispap...

Background: Compelling evidence has manifested a strong association between aberrant expression of long noncoding RNAs (lncRNAs) and gastric carcinoma (GC) development. Nonetheless, biological impacts differentially expressed lncRNAs (DElncRNAs) on GC are not scrutinized. Methods: Bioinformatics methods were employed for differential analysis target gene prediction. MTT, colony formation, Trans...

Objective(s): Apatinib recently has been used to treat patients with gastric cancer, but the function of apatinib in colon cancer remains unclear. This study was conducted to investigate the impacts of apatinib on the biological function and its potential mechanism of colon cancer cells in vitro. Materials and Methods:The effect of apatinib in colon cancer cells were detected by assessing cell ...

Objective(s): Ten-eleven translocation (TET) family members have been shown to be involved in the development of many tumors. However, the biological role of the TET family and its mechanism of action in colorectal carcinogenesis and progression remain poorly understood. Materials and Methods:We measured the expression levels of TET family members in colorectal cancer (CRC) specimens, in the c...

Biological invasion seriously threatens ecological stability and social development. One of the bases for forming is alien species’ strong phenotypic plasticity. Phenotypic plasticity can help species adapt to environmental changes enhance their invasive ability. China one countries affected by drought. Under background drought, exploring reasons why plants gain growth advantages mastering in r...

Aldehyde dehydrogenases (ALDH) is a family of enzymes including 19 members. For now, ALDH activity had been wildly used as a marker of cancer stem cells (CSCs). But biological functions of relevant isoforms and their clinical applications are still controversial. Here, we investigate the clinical significance and potential function of ALDH1A3 in gliomas. By whole-genome transcriptome microarray...

Biological fluids, such as blood and mucosal secretions, continuously flow within the human body and form prominent barriers to pathogen colonization and invasion of host cells [1, 2]. Consequently, pathogens have evolved sophisticated molecular strategies to overcome the mechanical shear forces associated with resisting the flow of biological fluids; in particular, membrane anchored biomolecul...