نتایج جستجو برای: bipolar

تعداد نتایج: 37978  

2016
Daniel Javitt USA Lakshmi N. Yatham Canada

Treatments for brain dysfunction have relied traditionally on medication-based approaches. Non-invasive transcranial electric stimulation (tES) approaches such as transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) offer an alternative approach for psychiatric treatment. In this approach, low level (1–2 mA) currents are applied over appropriate...

Journal: :The British journal of psychiatry : the journal of mental science 2016
Ming Li Xiong-jian Luo Mikael Landén Sarah E Bergen Christina M Hultman Xiao Li Wen Zhang Yong-Gang Yao Chen Zhang Jiewei Liu Manuel Mattheisen Sven Cichon Thomas W Mühleisen Franziska A Degenhardt Markus M Nöthen Thomas G Schulze Maria Grigoroiu-Serbanescu Hao Li Chris K Fuller Chunhui Chen Qi Dong Chuansheng Chen Stéphane Jamain Marion Leboyer Frank Bellivier Bruno Etain Jean-Pierre Kahn Chantal Henry Martin Preisig Zoltán Kutalik Enrique Castelao Adam Wright Philip B Mitchell Janice M Fullerton Peter R Schofield Grant W Montgomery Sarah E Medland Scott D Gordon Nicholas G Martin Marcella Rietschel Chunyu Liu Joel E Kleinman Thomas M Hyde Daniel R Weinberger Bing Su

BACKGROUND Bipolar disorder is a highly heritable polygenic disorder. Recent enrichment analyses suggest that there may be true risk variants for bipolar disorder in the expression quantitative trait loci (eQTL) in the brain. AIMS We sought to assess the impact of eQTL variants on bipolar disorder risk by combining data from both bipolar disorder genome-wide association studies (GWAS) and bra...

Journal: :Biological psychiatry 2000
J Biederman S V Faraone J Wozniak M C Monuteaux

BACKGROUND Bipolar disorder has emerged as a risk factor for substance use disorders (alcohol or drug abuse or dependence) in youth; however, the association between bipolar disorder and substance use disorders is complicated by comorbidity with conduct disorder. We used familial risk analysis to disentangle the association between the three disorders. METHODS We compared relatives of four pr...

Journal: :Journal of cardiovascular electrophysiology 2002
Hiroshi Tada Hakan Oral Bradley P Knight Mehmet Ozaydin Aman Chugh Christoph Scharf Sohail Hassan Radmira Greenstein Frank Pelosi S Adam Strickberger Fred Morady

INTRODUCTION Segmental ostial ablation to isolate pulmonary veins is guided by pulmonary vein potentials. The aim of this prospective randomized study was to compare the utility of unipolar plus bipolar electrograms versus only bipolar electrograms as a guide for segmental ablation to isolate the pulmonary veins in patients with atrial fibrillation. METHODS AND RESULTS Isolation of the left s...

2016
Yanli Zhao Wenbo Luo Jingxu Chen Dandan Zhang Ligang Zhang Chunling Xiao Fengmei Fan Xiaolin Zhu Hongzhen Fan Shuping Tan

Self-referential processing is a core component of social cognition. However, few studies have focused on whether self-referential processing deficits present in bipolar disorder. The current study combined a high-time-resolution event-related potential (ERP) technique with the self-referential memory (SRM) task to evaluate self-referential processing in 23 bipolar patients and 27 healthy contr...

Journal: :Clinical and experimental rheumatology 2012
Alessandra Alciati Piercarlo Sarzi-Puttini Alberto Batticciotto Riccardo Torta Felice Gesuele Fabiola Atzeni Jules Angst

OBJECTIVES To test the hypothesis that the premorbid overactivity previously described in subjects with fibromyalgia is a core feature of the manic/hypomanic symptoms characterising bipolar spectrum disorders. METHODS 110 consecutive patients with fibromyalgia were assessed for bipolar spectrum disorders using both categorical and dimensional approaches. The first was based on a version of th...

2015
Xavier Caseras Kevin Murphy Natalia S Lawrence Paola Fuentes-Claramonte Jessica Watts Derek K Jones Mary L Phillips

OBJECTIVES Emotion regulation deficits are a core feature of bipolar disorder. However, their potential neurobiological underpinnings and existence beyond bipolar I disorder remain unexplored. Our main goal was to investigate whether both individuals with bipolar I and bipolar II disorder show deficits in emotion regulation during an attention control task, and to explore the neurophysiological...

2017
Francisco Arias Nestor Szerman Pablo Vega Beatriz Mesías Ignacio Basurte David Rentero

Given its prevalence and impact on public health, the comorbidity of bipolar and substance use disorders is one of the most relevant of dual diagnoses. The objective was to evaluate the characteristics of patients from community mental health and substance abuse centres in Madrid. The sample consisted of 837 outpatients from mental health and substance abuse centres. We used the Mini Internatio...

Journal: :The British journal of psychiatry : the journal of mental science 2006
Carla Torrent Anabel Martínez-Arán Claire Daban Jose Sánchez-Moreno Mercè Comes José Manuel Goikolea Manel Salamero Eduard Vieta

BACKGROUND Persistent impairments in neurocognitive function have been described in bipolar disorder. AIMS To compare the cognitive performance of patients with bipolar II disorder with that of patients with bipolar I disorder and a healthy control group. METHOD The study included 71 euthymic patients with bipolar disorder (38 bipolar I, 33 bipolar II), who were compared on clinical and neu...

صالحی, منصور, علوی, کاوه , کمال‌زاده, لیلا ,

Objectives: To introduce a patient with bipolar disorder type1 who developed multiple paraphilic behavior. Case report: A 25 year old man with history of bipolar disorder type 1 along with paraphilic behaviors including frotteurism, fetishism, transvestism, voyeurism, and oppositional behaviors, lower than normal intelligence and possible history of attention deficit/hyperactivity disorder (ADH...

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