BACKGROUND Given the widespread reports involving the use of selective serotonin reuptake inhibitors (SSRIs) in children, the present paper reviews and discusses published double-blind, placebo-controlled studies assessing the safety and efficacy of SSRIs in children and adolescents with major depressive disorder. METHODS Published and unpublished double-blind, placebo-controlled studies of S...

AIM To determine the differences in outcome in a group of children with idiopathic intracranial hypertension (IIH) who do not present with headaches. METHODS Differences in epidemiological and aetiological factors, clinical presentation, and visual outcome were investigated in children with a diagnosis of IIH presenting with and without headaches to the Paediatric Neurology and Paediatric Oph...

It is known that blind children represent spatial environments with cognitive difficulty. This can be decreased if they are exposed to interactive experiences with acoustic stimuli delivered through spatialized sound software. A few studies have approached this issue by using interactive applications that integrate virtual reality and cognitive tasks to enhance spatial orientation skills. The a...

Associations between sensory features of different natures are defined as crossmodal correspondences. In the context size perception, low pitch sound frequencies often associated with larger objects and high smaller objects. Here we investigate such correspondences in sighted visually-impaired children. Experiment 1, after listening to sounds (250–5000 Hz pure tones), children aged 6–11 years w...

A double-blind controlled study of 14 preschool children with recurrent wheezing episodes was performed to show the effectiveness of nebulised sodium cromoglycate in inhibiting exercise-induced bronchoconstriction in this age group. All 14 children showed markedly less exercise-induced bronchoconstruction after nebulised sodium cromoglycate, 13 of them to a degree indistinguishable from results...

Methods In an open study design 460 children aged 5 to 30 months with AE and no detectable peanut-specific serum IgE will be divided into two groups. In Group A parents are advised to feed their children peanut at least three times a week, in Group B participating children strictly avoid peanut in their diet. Children are followed for one year. At the beginning and the end of the study standard...