Background: Finding a suitable method for rapid, accurate and reliable estimation of absorbed dose has high priority in management of the radiation exposed persons. Shortly after radiation exposure, apoptosis is a major detriment in proliferative tissues such as the hematopoietic system. Therefore, quantification of apoptosis in these tissues could be useful for rapid estimation of radiation ex...

due to the wide range of applications for ozone and its increasing use for medical and industrial purposes, studying its effects has become a very important line of research. the ozone has been suspected to be a carsinogen. because of the increasing use of ozone, the human could be more and more exposed to this gas. in this study the effects of ozone inhalation on chromosomes and its clastogeni...

background  in recent years, many researchers haveattempted to cure diabetes by using stem cells technology. stem cells from different sources have capabilityto differentiateinto insulin producing cells (ipcs) by different methods. the obstaclesof these methods aretheirexpensive materials and complexity ofmethodswhichare practicallydisadvantagesfor producing enough transplantableipcs that can c...

objective: bone marrow mesenchymal stem cells reside in bone marrow and support homing and differentiation of hematopoietic stem cells (1). this makes them an excellent instrument for regenerative treatment and co-culture with the hsc. materials and methods: in this study, k562 cell lines were treated with butyric acid(for erythroid differentiation), co-cultured with mesenchymal stem cells and ...

bone tissue engineering has been one of the most promising areas of research, providing a potential clinical application to cure bone defects. recently, various stem cells, including embryonic stem cells (escs), bone marrow-derived mesenchymal stem cells (bm-mscs), umbilical cord blood-derived mesenchymal stem cells (ucb-mscs), adipose tissue-derived stem cells (adscs), muscle-derived stem cell...

introduction: bone marrow contains a population of stem cells capable of differentiating to osteoblast and forming the bone nodule by dexamethasone. material and methods: the stromal cells of bone marrow obtained from 4 to 6 weeks old spruge-dawely male rats were grown in primary culture for 7 days and subcultured for 18 days. the cells were cultured in either dmem medium containing 15% fetal c...

Human prostate cancer frequently metastasizes to bone marrow. What defines the cellular and molecular predilection for prostate cancer to metastasize to bone marrow is not well understood. CD4(+)CD25(+) regulatory T (Treg) cells contribute to self-tolerance and tumor immune pathology. We now show that functional Treg cells are increased in the bone marrow microenvironment in prostate cancer pat...

introduction: an induction of osteogenic differentiation in rat bone marrow stromal cell cultures by dexamethasone was reported. materials and methods: the marrow stromal cells obtained from 4 to 6 weeks - old spruge-dawely male rats were grown in primary culture for 7 days and then subcultured for 20 days. the cells were cultured in either dmem medium containing 15% fetal calf serum, antibioti...