Background: Human leukocyte antigens (HLAs) are found to be significant genetic factors concerning the susceptibility of an individual to certain diseases. Objective: To determine the association between variants of class I (A and B) and class II (DRB1) HLA alleles and chronic renal failure (CRF), compared with healthy controls, in Yemen. Methods: A case-control study in the Urology and Nephrol...

Several genome-wide searches for disease-associated gene variations have been recently reported (Spinola et al, 2006; Herbert et al, 2006). However, complex diseases can be caused by combinations of several unlinked gene variations. Unfortunately, an exhaustive search among all possible corresponding multi-SNPs can be unfeasible even for small number of SNPs let alone the complete genome. Disea...

Background: The traditional methods of studying the gene-environment interactions need a control group. However, the selection of an appropriate control group has been associated with problems. Therefore, new methods, such as case-only design, have been created to study such interactions. The objective of this study was to compare the case-only and case-control designs using data from patients ...

atopy can be defined as the genetically determined risk to develop allergic disease. avoidance of one specific allergen may decrease the risk for sensitization against this allergen, but it will not affect atopy. our aim was to investigate if exclusive breast-feeding is associated with atopic dermatitis during the first 5 years of life. data on 200 children were taken from parental-administered...

The FAIR control system (CS) is an alarm-based design and employs White Rabbit time synchronization over a GbE network to issue commands executed accurate to 1 ns. In such a network based CS, graphs of possible machine command sequences are specified in advance by physics frameworks. The actual traffic pattern, however, is determined at runtime, depending on interlocks and beam requests from ex...