By far the main focus of contemporary wine tourism research has been in 'New World' regions, while it appears to be under development in much of the 'Old World.' Th e present study adds to this underdeveloped body of research in that it addresses a range of wine tourism development issues, across three prominent 'Old World' wine regions: La Mancha, La Rioja and Penedès. A total of 94 wineries p...

The New York Bight extends seaward some 80 to 100 miles (ca. 129 to 161 km) from the Long Island and New Jersey shorelines to the edge of the continental shelf. Over 14 x 10(6) m(3) of sewage sludge, dredge spoils, acid wastes, and cellar dirt are discharged into this area each year. Large populations of Bacillus sp. resistant to 20 mug of mercury per ml were observed in Bight sediments contami...

Artificial rainwater harvesting system (ARHS) is a new way to increase water supply in semi-arid area, and has developed rapidly recent years in northwestern China. Not only it used in domestic supply, but also in agricultural as supply irrigation. More than 2 million water cellars have been built in Loess Plateau of China. In this paper, based on 5 years’ related experiments, field engineering...

The long-time studies on wine yeasts have determined a wide diffusion of inoculated fermentations by commercial starters, mainly of Saccharomyces. Although the use of starter cultures has improved the reproducibility of wine quality, the main drawback to this practice is the lack of the typical traits of wines produced by spontaneous fermentation. These findings have stimulated wine-researchers...

In this study, we report the role of DNA methyltransferase 1 (DNMT1) in ultraviolet A (UVA)-induced senescence in human dermal fibroblasts (HDFs). We show that DNMT1 expression was significantly reduced during UVA-induced senescence, and this senescence could be alleviated or aggravated by the up- or down-regulation of DNMT1, respectively. Expression of the transcription factor zinc finger E-bo...

Expression of receptor tyrosine-kinase (RTK) EGFR is low in normal prostate, but increases in prostate cancer. This receptor is significantly up-regulated as tumors progress into higher grade, androgen-insensitive and metastatic lesions. The up-regulated receptors could serve as targets for novel selective anti-cancer drugs, e.g. antibodies and tyrosine kinase inhibitors. Radionuclide imaging o...

BACKGROUND Fungi have been known to cause a variety of respiratory conditions, ranging from mold- associated asthma to allergic bronchopulmonary mycosis and invasive disease. More recently some fungal species have been implicated in a non-asthmatic chronic cough syndrome. CASE PRESENTATION A 59-year-old male presented to the pulmonary clinic with chronic nonproductive cough. Workup included p...

Ubiquitination is a post-translational modification that is involved in myriad cellar regulation and disease pathways. The ubiquitin-conjugating enzyme (E2) is an important player in the ubiquitin transfer pathway. Although many E2 structures are available, not all E2 families have known structures, and three-dimensional structures from fungal organisms other than yeast are lacking. We report h...

Article history: Received: 11.03.2013. Received in revised form: 02.04.2013. Accepted: 02.04.2013. This paper puts forward an innovative criterion in the cellar automata (CA) technique for both matching zone similarity and mapping failure pattern of masonry wall panel. The criterion proposed in this paper is a two-step matching method. Firstly, calculate the state values of the cells in the bas...

WHAT THIS SHEET APPLIES TO Anyone using Strider Theater, the Cellar Theater, and the Scene Shop for electrical or stage lighting needs. • Only trained and authorized electricians should remove covers from electrical panels. • Only properly trained and authorized persons are allowed to work with stage lighting equipment and electrical equipment. • All tools and lighting equipment must be UL list...