Objective: The objective of the present study was to develop and optimize Astragalin-loaded polymeric nanoparticles (AST-NPs) using a central composite factorial design (CCD). Methods: AST-NPs were prepared by dialysis method. CCD employed influence formulation factors, polymer concentration, aqueous organic phase ratio, process parameter stirring time on dependent physicochemical characteristi...

In this work, perlite was used as a low-cost source of Si and Al in the synthesis of sodalite zeolite using hydrothermal synthesis method. Cu2O nanoparticles were coated on a bed of sodalite zeolite and used as an adsorbent for removal of diazinon from aqueous solutions. To analyze the process, a significant variable .i.e. removal efficiency (%) of diazinon and three dependent parameters as the...

The effect of substrate concentration, pH and cultivation time on the production of endoxylanase from Aspergillus awamori ZH-26 were optimized by statistical analysis using response surface methodology (RSM). Endoxylanase production was optimized by central composite rotary design. Statistical analysis of the results showed that the linear and quadratic terms of these three variables had signif...

Air infiltration in mass scale industrial applications of bio char production is inevitable. The presence of oxygen during the carbonization process is detrimental to the production of biochar yield and properties. The experiment was carried out on several wood species in a fixed-bed pyrolyser under various fractions of oxygen ranging from 0% to 11% by varying nitrogen and oxygen composition in...

The objective of this paper is to study the effect of the various process parameters i.e. peak current, noload voltage, pulse on time and duty cycle on response parameters by mixing silicon powder in the dielectric fluid of the Electric Discharge Machining (EDM). Response surface methodology (RSM) is used for investigating the effect on these parameters. Central composite design (CCD) is used f...

A thermoplastically extruded snack was produced from different blends of corn grits and silver carp minced meat. Response Surface Methodology (RSM) was used to study the effect of fish meat content and to optimize the feed composition. Fourteen treatments from central composite design considering minced fish content (0-3 kg) and corn (7-10 kg) were used as the independent variables. The expansi...

response surface methodology (rsm) was used in order to find the suitable conditions of ultrasonic treatment for achieving the maximum inactivation rate and anthocynins content during ultrasonic processing of red grape juice. temperature in 3 levels (25 - 37.5 - 50°c), time in (20 – 30 - 40 minutes) and frequency (0 - 67.5 – 135 khz) were parameters which effects were studied. experiments were ...