BACKGROUND This study examined potential associations between exposure to episodes of air pollution and alterations in semen quality. The air pollution, resulting from combustion of coal for industry and home heating in the Teplice district of the Czech Republic, was much higher during the winter than at other times of year with peaks exceeding US air quality standards. METHODS Young men from...

Polymer physics, comparing ways to assess chromatin structure and taking in tales at the Italian seaside.

Colorectal cancer (CRC) is the third leading cause of death in western world. In women, menopausal hormone therapy has been shown to reduce CRC incidence by 20%. Studies demonstrate that estrogen activating receptor beta (ERβ) protects against CRC. ERβ a nuclear regulates gene expression through interactions with chromatin. This molecular mechanism is, however, not well characterized colon. Her...

SUMMARY Histone chaperones mediate the assembly and disassembly of nucleosomes participate in essentially all DNA‐dependent cellular processes. In Arabidopsis thaliana , loss‐of‐function FAS1 or FAS2 subunits H3‐H4 histone chaperone complex CHROMATIN ASSEMBLY FACTOR 1 (CAF‐1) has a dramatic effect on plant morphology, growth overall fitness. CAF‐1 dysfunction can lead to altered chromatin compa...

introduction: the novel development of the (hba) sperm- hyaluronan binding assay has now been routinely used in some laboratories worldwide to predict sperm maturity and functionality. the purpose of this study was to evaluate the correlation between hba score and histone deficiency, protamine content and dna fragmentation. methods: during april- march 2012 patients who were enrolled at shiraz-...