Biopolymers such as carrageenan or collagen can be used carriers for loading a drug to enhance drug’s bioavailability. In this work, allopurinol was loaded on carrageenan/collagen blend and the carrageenan/collagen/allopurinol (CCA) biocomposite films were prepared using ionic gelation method combined with 3D printing gel ink material. The advantages of are ease in shaping design controlling th...

Background and Objective: Umbilical Cord blood (UCB) hematopoietic stem cell (HSC) transplantation is a therapeutic approach for the treatment of malignant and non-malignant hematologic disorders due to ease of collection, lack of risk for donors and lower levels of infection. Moreover, it is considered a good alternative for bone marrow HSC transplantation. The main limitation of their use is ...

Background and Objectives: Accelerating wound healing is a very important factor for patients to return to ordinary life. Laser seems to have positive effect on cutaneous wound healing. This study aimed to investigate the effect of red light laser 630 nm on cutaneous surgical wound in hamster and to compare outcomes such as angiogenesis, number of fibroblasts and collagen form...

Background: Cysteine proteases of the liver fluke, Fasciola hepatica, participate in catabolism of proteins, migration of the fluke through host tissues and combat host immune system. Objectives: In this study, we evaluated proteolytic activity of F. hepatica recombinant cathepsin L1 (rCL1) against gelatin and collagen as common substrat...

tumors that originate from the nerve sheath comprise diverse groups -perineuroma, neurofibroma and schwannoma. the epithelioid variant of these tumors is uncommon and mostly seen in malignant counterparts. although this type of morphology is well recognized in peripheral nerve sheath tumors, its presence in the central nerves is rarely reported. very few cases of nerve sheath tumors have been r...

BACKGROUND In fibrotic diseases such as pulmonary fibrosis there is evidence suggesting enhanced synthesis and degradation of lung connective tissue components, including collagen. It has therefore been hypothesised that products of collagen degradation may have a role in the promotion of collagen deposition. In support of this hypothesis, it has recently been shown that intravenous injection o...